Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18839622 | 0.79 | GAA (0.39) | GAAALDH1A1RECQLDUTCYP1A2 | |
| SCHEMBL9544542 | 0.79 | GAA (0.58) | GAAALDH1A1RECQLDUTCYP1A2 | |
| SCHEMBL18839737 | 0.77 | ALDH1A1 (0.41) | GAAALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL4851745 | 0.76 | RECQL (0.55) | GAAALDH1A1RECQLDUTCYP1A2 | |
| SCHEMBL12767494 | 0.76 | GAA (0.51) | GAAALDH1A1RECQLDUTCYP1A2 | |
| SCHEMBL31712151 | 0.75 | GAA (0.67) | GAAALDH1A1RECQLDUTCYP1A2 | |
| SCHEMBL18839862 | 0.75 | GAA (0.50) | GAAALDH1A1RECQLCYP1A2MEN1 | |
| SCHEMBL18839673 | 0.75 | GAA (0.40) | GAAALDH1A1RECQLDUTCYP1A2 | |
| SCHEMBL18839790 | 0.75 | GAA (0.48) | GAAALDH1A1RECQLCYP1A2HTT | |
| SCHEMBL18839649 | 0.74 | HSP90AB1 (0.49) | GAAALDH1A1RECQLMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017081615-A1 | 7-OXO -6-(SULFOOXY)- 1,6-DIAZABICYCLO [3.2.1] OCTANE CONTAINING COMPOUNDS AND THEIR USE IN TREATMENT OF BACTERIAL INFECTIONS | WOCKHARDT LIMITED (IN) | 2017-05-18 | — | — | WO | disclosed |