Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3253975 | 0.81 | HSD17B10 (0.47) | TDP1GPR35CUL4AKMT2AMAPT | |
| SCHEMBL31525035 | 0.81 | HSD17B10 (0.47) | TDP1GPR35CUL4AKMT2AMAPT | |
| SCHEMBL27973468 | 0.80 | TDP1 (0.45) | TDP1GPR35KMT2AMAPTMEN1 | |
| SCHEMBL27296357 | 0.79 | TDP1 (0.46) | TDP1KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL18184967 | 0.79 | TDP1 (0.62) | TDP1GPR35KMT2AMAPTMEN1 | |
| SCHEMBL28522110 | 0.79 | TDP1 (0.44) | TDP1GPR35KMT2AMAPTMEN1 | |
| SCHEMBL65199 | 0.78 | TDP1 (0.61) | TDP1GPR35KMT2AMAPTMEN1 | |
| SCHEMBL28189442 | 0.77 | TDP1 (0.44) | TDP1GPR35KMT2AMAPTMEN1 | |
| SCHEMBL18863544 | 0.76 | TDP1 (0.41) | TDP1GPR35KMT2AMAPTMEN1 | |
| SCHEMBL18863587 | 0.76 | TDP1 (0.41) | TDP1GPR35KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116063283-B | 3-Amino indazole compound and application thereof | 暨南大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-116063283-A | 3-amino indazole compound and application thereof | 暨南大学 | 2023-05-05 | — | — | CN | disclosed |
| CN-108348504-B | Compound with HCV (hepatitis C Virus) inhibiting activity as well as preparation method and application thereof | 江苏豪森药业集团有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-108348504-A | Compound with HCV (hepatitis C Virus) inhibiting activity as well as preparation method and application thereof | 江苏豪森药业集团有限公司 | 2018-07-31 | — | — | CN | disclosed |
| WO-2017076194-A1 | COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST HCV, PREPARATION METHOD AND USE THEREOF | 江苏豪森药业集团有限公司 | 2017-05-11 | — | — | WO | disclosed |