SCHEMBL31525035

SCHEMBL31525035

O=[N+]([O-])c1ccccc1C1CC1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
KDM4E B2RXH2 2/20 0.46
MAPT P10636 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
GAA P10253 1/20 0.46
HTT P42858 1/20 0.46
ALDH1A1 P00352 6/20 0.46
CUL4A Q13619 1/20 0.45
TDP1 Q9NUW8 5/20 0.45
GPR35 Q9HC97 1/20 0.43
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3253975 1.00 HSD17B10 (0.47) HSD17B10MEN1KMT2AKDM4EMAPT
SCHEMBL28316412 0.92 ALDH1A1 (0.47) HSD17B10MEN1KMT2AKDM4EMAPT
SCHEMBL1065970 0.92 MEN1 (0.47) HSD17B10MEN1KMT2AKDM4EMAPT
SCHEMBL7335158 0.90 HSP90AA1 (0.49) HSD17B10MEN1KMT2AKDM4EMAPT
SCHEMBL8748376 0.87 HTR2C (0.51) MEN1KMT2AKDM4EMAPTL3MBTL1
SCHEMBL9349844 0.83 ALDH1A1 (0.42) HSD17B10MEN1KMT2AKDM4EMAPT
SCHEMBL9349842 0.83 ALDH1A1 (0.42) HSD17B10MEN1KMT2AKDM4EMAPT
SCHEMBL27973468 0.82 TDP1 (0.45) HSD17B10MEN1KMT2AKDM4EMAPT
SCHEMBL28522110 0.81 TDP1 (0.44) HSD17B10MEN1KMT2AKDM4EMAPT
SCHEMBL18840407 0.81 TDP1 (0.44) HSD17B10MEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4545515-A1 BCL-2 INHIBITORS BeiGene Switzerland GmbH (CH) 2025-04-30 EP disclosed