Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886318 | 0.85 | ALDH1A1 (0.36) | TDP1ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL5886320 | 0.85 | ALDH1A1 (0.36) | TDP1ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL5886424 | 0.82 | PDE4B (0.36) | TDP1ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL5886428 | 0.82 | PDE4B (0.36) | TDP1ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL3253975 | 0.81 | HSD17B10 (0.47) | TDP1GPR35ALDH1A1KDM4EKMT2A | |
| SCHEMBL31525035 | 0.81 | HSD17B10 (0.47) | TDP1GPR35ALDH1A1KDM4EKMT2A | |
| SCHEMBL27973468 | 0.80 | TDP1 (0.45) | TDP1GPR35ALDH1A1KDM4EKMT2A | |
| SCHEMBL18840407 | 0.79 | TDP1 (0.44) | TDP1GPR35ALDH1A1KDM4EKMT2A | |
| SCHEMBL18184967 | 0.79 | TDP1 (0.62) | TDP1GPR35KMT2AMAPTMEN1 | |
| SCHEMBL31090476 | 0.78 | TDP1 (0.40) | TDP1GPR35ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848598-B | Heterocyclic compound, application thereof and composition containing same | 健艾仕生物医药有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-111848598-A | Heterocyclic ring-containing compound, application thereof and composition containing heterocyclic ring-containing compound | 健艾仕生物医药有限公司 | 2020-10-30 | — | — | CN | disclosed |