Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.48 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.48 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.47 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18855472 | 0.93 | POLB (0.51) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL18844349 | 0.89 | P2RX3 (0.58) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL18840495 | 0.89 | P2RX3 (0.58) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL24858837 | 0.88 | P2RY1 (0.54) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL18844358 | 0.87 | PRMT5 (0.39) | POLBENPP1DTYMK | |
| SCHEMBL21191343 | 0.84 | POLB (0.48) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL22858579 | 0.84 | POLB (0.48) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL19174555 | 0.82 | AHCY (0.48) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL19662415 | 0.82 | POLB (0.47) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL20821469 | 0.81 | POLB (0.50) | POLBP2RY1ENPP1P2RY2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017079498-A2 | NUCLEOTIDE ANALOGUES | INTELLIGENT BIOSYSTEMS, INC. (US) | 2017-05-11 | — | — | WO | disclosed |