Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 17/20 | 0.73 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18840885 | 0.85 | CCR3 (1.00) | CCR3 | |
| SCHEMBL18844416 | 0.85 | CCR3 (1.00) | CCR3 | |
| SCHEMBL18840860 | 0.79 | CCR3 (1.00) | CCR3 | |
| SCHEMBL18840901 | 0.73 | CCR3 (1.00) | CCR3 | |
| SCHEMBL18840818 | 0.72 | CCR3 (1.00) | CCR3 | |
| SCHEMBL18840857 | 0.72 | CCR3 (1.00) | CCR3 | |
| SCHEMBL18840888 | 0.71 | CCR3 (1.00) | CCR3 | |
| SCHEMBL18840845 | 0.66 | CCR3 (1.00) | CCR3 | |
| SCHEMBL30671730 | 0.66 | SIGMAR1 (0.73) | CCR3SIGMAR1 | |
| SCHEMBL26358361 | 0.65 | SLC6A4 (0.52) | CCR3SIGMAR1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170131282-A1 | Inhibition of Chemokine CCL7 or Receptor CCR3 of Same for the Treatment and Diagnosis of Prostate Cancer | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2017-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170131282-A1 | Inhibition of Chemokine CCL7 or Receptor CCR3 of Same for the Treatment and Diagnosis of Prostate Cancer | CCR3, CCR5, CCR1 | CCR3 1/4885SIGMAR1 2400/4885MC4R 1166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.