Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417921 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2NFE2L2CA12CA1CA2 | |
| SCHEMBL31438691 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2NFE2L2CA12CA1CA2 | |
| SCHEMBL18537139 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2NFE2L2CA12CA1CA2 | |
| SCHEMBL5164827 | 0.80 | NFE2L2 (0.44) | SMN1; SMN2NFE2L2CA12CA1CA2 | |
| SCHEMBL27615074 | 0.78 | NFE2L2 (0.42) | SMN1; SMN2NFE2L2CA12CA1CA2 | |
| SCHEMBL10451316 | 0.78 | AR (0.49) | SMN1; SMN2NFE2L2CA12CA1CA2 | |
| SCHEMBL29749364 | 0.78 | AR (0.49) | SMN1; SMN2NFE2L2CA12CA1CA2 | |
| SCHEMBL20153912 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2NFE2L2CA12CA1CA2 | |
| SCHEMBL18493200 | 0.77 | NFE2L2 (0.44) | SMN1; SMN2NFE2L2CA12CA1CA2 | |
| SCHEMBL67886 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2NFE2L2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090260-A1 | Multiplexed Assay Using Spectrally-Encoded Solid Support Matrices | IRORI TECHNOLOGIES, INC. (US) | 2013-04-11 | — | — | US | disclosed |
| US-20120238466-A1 | Multiplexed Assay Using Encoded Solid Support Matrices | IRORI TECHNOLOGIES, INC. (US) | 2012-09-20 | — | — | US | disclosed |
| US-8219327-B2 | Multiplexed assay using encoded solid support matrices | IRORI TECHNOLOGIES, INC. (US) | 2012-07-10 | — | — | US | disclosed |
| US-20110237459-A1 | Multiplexed Assay Using Encoded Solid Support Matrices | NEXUS BIOSYSTEMS, INC. (US) | 2011-09-29 | — | — | US | disclosed |
| US-20110212857-A1 | Multiplexed Assay Using Encoded Solid Support Matrices | NEXUS BIOSYSTEMS, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| US-7935659-B2 | Multiplexed assays using encoded solid supports | NEXUS BIOSYSTEMS, INC. (US) | 2011-05-03 | — | — | US | disclosed |
| US-20090226891-A2 | ENCODED SOLID SUPPORTS FOR BIOLOGICAL PROCESSING AND ASSAYS USING SAME | NEXUS BIOSYSTEMS, INC. (US) | 2009-09-10 | — | — | US | disclosed |
| US-20070248957-A1 | Encoded solid supports for biological processing and assays using same | NEXUS BIOSYSTEMS, INC. | 2007-10-25 | — | — | US | disclosed |
| US-6955915-B2 | Apparatus comprising polymers | AFFYMETRIX, INC. (US) | 2005-10-18 | — | — | US | disclosed |
| US-20050208537-A1 | Very large scale immobilized polymer synthesis | AFFYMETRIX, INC. (US) | 2005-09-22 | — | — | US | disclosed |
| US-5550215-A | FORMING POLYMER ON SUBSTRATE WITH A TETHER MOLECULE; CYCLIZATION; DEPROTECTING; DECYCLIZATION | AFFYMETRIX, INC. | 1996-08-27 | — | — | US | disclosed |
| US-5549974-A | IMMOBILIZATION | AFFYMAX TECHNOLOGIES NV (AN) | 1996-08-27 | — | — | US | disclosed |
| WO-1996020725-A2 | PEPTIDE, PEPTIDE ANALOG AND AMINO ACID ANALOG PROTEASE INHIBITORS | SIBIA NEUROSCIENCES, INC. (US) | 1996-07-11 | — | — | WO | disclosed |
| US-5527681-A | Immobilized molecular synthesis of systematically substituted compounds | AFFYMAX TECHNOLOGIES N.V. (NL) | 1996-06-18 | — | — | US | disclosed |
| WO-1996000148-A1 | METHODS FOR THE SOLID PHASE SYNTHESIS OF THIAZOLIDINONES, METATHIAZANONES, AND DERIVATIVES THEREOF | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-01-04 | — | — | WO | disclosed |
| WO-1995018971-A1 | METHODS FOR THE SOLID PHASE SYNTHESIS OF GLYCOCONJUGATES | AFFYMAX TECHNOLOGIES N.V. (NL) | 1995-07-13 | — | — | WO | disclosed |
| US-5424186-A | Biosynthesis of oligonucleotides on solid substrate by irradiation of predefined segments to remove blocking agents; then coupling with nucleotide | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-06-13 | — | — | US | disclosed |
| WO-1994010128-A1 | NOVEL PHOTOREACTIVE PROTECTING GROUPS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1994-05-11 | — | — | WO | disclosed |
| US-5242974-A | Polymer formation on substrate with tether molecule, unmasking of protective group to form cyclic polymer, bond clevage | AFFYMAX TECHNOLOGIES N.V. (NL) | 1993-09-07 | — | — | US | disclosed |
| WO-1993010161-A1 | POLYMER REVERSAL ON SOLID SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1993-05-27 | — | — | WO | disclosed |