Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | GLP1R | P43220 | 1/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3887537 | 1.00 | CCR2 (1.00) | CCR2ADRB2HRH1DRD3GLP1R | |
| SCHEMBL3887539 | 1.00 | CCR2 (1.00) | CCR2ADRB2HRH1DRD3GLP1R | |
| SCHEMBL3897520 | 0.92 | CCR2 (0.85) | CCR2ADRB2HRH1DRD3GLP1R | |
| SCHEMBL3897521 | 0.92 | CCR2 (0.85) | CCR2ADRB2HRH1DRD3GLP1R | |
| SCHEMBL3890073 | 0.91 | CCR2 (0.83) | CCR2ADRB2HRH1DRD3GLP1R | |
| SCHEMBL3890077 | 0.91 | CCR2 (0.83) | CCR2ADRB2HRH1DRD3GLP1R | |
| SCHEMBL3888582 | 0.90 | CCR2 (0.82) | CCR2ADRB2HRH1DRD3GLP1R | |
| SCHEMBL3888583 | 0.90 | CCR2 (0.82) | CCR2ADRB2HRH1DRD3GLP1R | |
| SCHEMBL3885278 | 0.88 | CCR2 (0.79) | CCR2ADRB2HRH1DRD3GLP1R | |
| SCHEMBL3885273 | 0.88 | CCR2 (0.79) | CCR2ADRB2HRH1DRD3GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10401365-B2 | Inhibition of chemokine CCL7 or receptor CCR3 of same for the treatment and diagnosis of prostate cancer | UNIVERSITE PAUL SABATIER (TOULOUSE III) (FR) | 2019-09-03 | — | — | US | disclosed |
| US-20170131282-A1 | Inhibition of Chemokine CCL7 or Receptor CCR3 of Same for the Treatment and Diagnosis of Prostate Cancer | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2017-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170131282-A1 | Inhibition of Chemokine CCL7 or Receptor CCR3 of Same for the Treatment and Diagnosis of Prostate Cancer | CCR3, CCR5, CCR1 | CCR2 5/4885ADRB2 1050/4885HRH1 1795/4885 |
| US-10401365-B2 | Inhibition of chemokine CCL7 or receptor CCR3 of same for the treatment and diagnosis of prostate cancer | CCR3, CCR5, CCR1 | CCR2 5/4885ADRB2 1077/4885HRH1 1870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.