Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CA6 | P23280 | 5/20 | 0.44 |
| ▸ | CA7 | P43166 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA4 | P22748 | 4/20 | 0.44 |
| ▸ | CA5A | P35218 | 4/20 | 0.44 |
| ▸ | CA3 | P07451 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13818638 | 0.90 | CA12 (0.46) | CA12CA6CA7CA9CA14 | |
| SCHEMBL15095723 | 0.82 | CA12 (0.32) | CA12CA6CA7CA9CA14 | |
| SCHEMBL16587425 | 0.82 | CA12 (0.42) | CA12CA6CA7CA9CA14 | |
| SCHEMBL8459269 | 0.80 | NFKB1 (0.30) | — | |
| Methyl Alcohol SCHEMBL28118451 | 0.79 | CA12 (0.44) | CA12CA6CA7CA9CA14 | |
| SCHEMBL9111117 | 0.79 | CA12 (0.39) | CA12CA6CA7CA9CA14 | |
| SCHEMBL5711364 | 0.78 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL5891867 | 0.78 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL19549 | 0.78 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL15472465 | 0.78 | CA12 (0.32) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2669269-B1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2019-05-22 | — | — | EP | disclosed |
| US-20170129987-A1 | CROSSLINKING CATALYST COMPRISING SILOXANE STRUCTURAL UNITS | SIKA TECHNOLOGY AG (CH) | 2017-05-11 | — | — | US | disclosed |