SCHEMBL8459269

SCHEMBL8459269

CO[Si](O)(CCCN)OC

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18923793 0.84 CYP1A2 (0.32)
SCHEMBL15472467 0.84
SCHEMBL18844339 0.80 CA12 (0.44)
SCHEMBL13818638 0.80 CA12 (0.46)
SCHEMBL4069273 0.79
SCHEMBL14505798 0.78
SCHEMBL15483718 0.77
SCHEMBL16078707 0.77
SCHEMBL10354482 0.77
SCHEMBL15679851 0.76 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0628615-B1 Method for coating using molten organosiloxane compositions DOW CORNING (US) 1999-03-03 EP claimed
EP-0628615-A1 Method for coating using molten organosiloxane compositions DOW CORNING CORPORATION (US) 1994-12-14 EP claimed
US-5352491-A In the presence of moisture, the flow transition temperature gradually increases due to reaction of hydrolyzable groups; forms non-flowable resin reinforced elastomer DOW CORNING CORPORATION (US) 1994-10-04 US claimed
EP-3271067-B1 GUANIDINE-FUNCTIONALIZED PERLITE PARTICLES, ARTICLES CONTAINING THE PARTICLES, AND METHODS OF USING THE PARTICLES AND ARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2020-10-21 EP disclosed
EP-2928900-B1 GUANIDINE-FUNCTIONALIZED PARTICLES AND METHODS OF MAKING AND USING 3M INNOVATIVE PROPERTIES CO (US) 2019-01-02 EP disclosed
EP-3084058-B1 LAMINATED ARTICLES FOR MICROBIAL REMOVAL AND LOW PRESSURE DROP FILTRATION, METHODS OF MAKING, AND METHODS OF USING SAME 3M INNOVATIVE PROPERTIES CO (US) 2017-11-08 EP disclosed
US-20170267703-A1 METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-09-21 US disclosed
US-9751901-B2 Method for preparing a polyorganosiloxane and a polyorganosiloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-09-05 US disclosed
US-20170197193-A1 MICROARRAY FABRICATION SYSTEM AND METHOD ILLUMINA, INC. 2017-07-13 US disclosed
US-20170192374-A1 INTERMEDIATE TRANSFER MEMBERS FOR USE WITH INDIRECT PRINTING SYSTEMS AND PROTONATABLE INTERMEDIATE TRANSFER MEMBERS FOR USE WITH INDIRECT PRINTING SYSTEMS LANDA CORPORATION LTD. (IL) 2017-07-06 US disclosed
US-20170088566-A1 METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-03-30 US disclosed
US-20130096288-A1 siRNA conjugate and preparation method thereof BIONEER CORPORATION (KR) 2013-04-18 US disclosed
US-20130096288-A1 siRNA conjugate and preparation method thereof BIONEER CORPORATION (KR) 2013-04-18 US disclosed
US-20120229884-A1 CHARGED PARTICLES BASF SE (DE) 2012-09-13 US disclosed
US-20120029166-A1 LINKERS AND CO-COUPLING AGENTS FOR OPTIMIZATION OF OLIGONUCLEOTIDE SYNTHESIS AND PURIFICATION ON SOLID SUPPORTS THE REGENTS OF THE UNVERSITY OF MICHIGAN (US) 2012-02-02 US disclosed
EP-0835289-B1 AMINOSILANE SALTS AND SILANAMIDES OF CARBOXYLIC ACIDS AS CORROSION INHIBITORS CIBA GEIGY AG (CH) 1999-05-19 EP disclosed
US-5879436-A REACTION PRODUCT OF CARBOXYLIC ACID AND AMINOSILANE; PROTECTIVE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-03-09 US disclosed
EP-0628615-B1 Method for coating using molten organosiloxane compositions DOW CORNING (US) 1999-03-03 EP disclosed
EP-0835289-A1 AMINOSILANE SALTS AND SILANAMIDES OF CARBOXYLIC ACIDS AS CORROSION INHIBITORS Ciba SC Holding AG (CH) 1998-04-15 EP disclosed
WO-1997001606-A1 AMINOSILANE SALTS AND SILANAMIDES OF CARBOXYLIC ACIDS AS CORROSION INHIBITORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-01-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170088566-A1 METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE SCO2, HAO2, RPS4X NFKB1 2879/4885
US-20170267703-A1 METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE SCO2, HAO2, RIOX2 NFKB1 3144/4885
US-20120029166-A1 LINKERS AND CO-COUPLING AGENTS FOR OPTIMIZATION OF OLIGONUCLEOTIDE SYNTHESIS AND PURIFICATION ON SOLID SUPPORTS PCNA, LIG4, DCLRE1A NFKB1 2511/4885
US-20120229884-A1 CHARGED PARTICLES POLE3, POLD3, IPO4 NFKB1 3223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.