Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18844746 | 0.82 | HPGD (0.57) | SAE1UBA2RAB9ANPC1HPGD | |
| SCHEMBL19043004 | 0.81 | SAE1 (0.55) | SAE1UBA2RAB9ANPC1HPGD | |
| SCHEMBL22550502 | 0.79 | SMN1; SMN2 (0.59) | SAE1UBA2RAB9ANPC1HPGD | |
| SCHEMBL22550572 | 0.79 | SMN1; SMN2 (0.59) | SAE1UBA2RAB9ANPC1HPGD | |
| SCHEMBL22793353 | 0.79 | SMN1; SMN2 (0.59) | SAE1UBA2RAB9ANPC1HPGD | |
| SCHEMBL14668125 | 0.77 | TSHR (0.56) | SAE1UBA2RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL19216513 | 0.77 | SAE1 (0.64) | SAE1UBA2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22550493 | 0.76 | SMN1; SMN2 (0.52) | RAB9ANPC1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL22550562 | 0.76 | SMN1; SMN2 (0.52) | RAB9ANPC1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL22550530 | 0.76 | SMN1; SMN2 (0.52) | RAB9ANPC1HPGDSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210324132-A1 | OXAZOLIDINEDIONE-TERMINATED PREPOLYMER | HUNTSMAN INTERNATIONAL LLC | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210324132-A1 | OXAZOLIDINEDIONE-TERMINATED PREPOLYMER | HPD, PCNA, HAAO | SAE1 4039/4885UBA2 1412/4885RAB9A 3111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.