Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915402 | 0.90 | KMT2A (0.65) | SIGMAR1DRD2KCNA3KMT2AL3MBTL1 | |
| SCHEMBL29608184 | 0.88 | KMT2A (0.52) | SIGMAR1DRD2KCNA3KMT2AL3MBTL1 | |
| SCHEMBL555464 | 0.85 | KMT2A (0.64) | SIGMAR1DRD2KCNA3KMT2AL3MBTL1 | |
| SCHEMBL5789230 | 0.84 | KMT2A (0.59) | SIGMAR1DRD2KCNA3KMT2AL3MBTL1 | |
| SCHEMBL12011087 | 0.84 | KMT2A (0.57) | SIGMAR1KCNA3KMT2AL3MBTL1MEN1 | |
| SCHEMBL27226915 | 0.84 | SIGMAR1 (0.59) | SIGMAR1DRD2KCNA3KMT2AL3MBTL1 | |
| SCHEMBL15021069 | 0.84 | SIGMAR1 (0.59) | SIGMAR1DRD2KCNA3KMT2AL3MBTL1 | |
| SCHEMBL29260128 | 0.84 | KCNA3 (0.53) | SIGMAR1DRD2KCNA3KMT2AL3MBTL1 | |
| SCHEMBL7549641 | 0.83 | KCNA3 (0.59) | SIGMAR1DRD2KCNA3KMT2AL3MBTL1 | |
| SCHEMBL3892168 | 0.83 | KMT2A (0.61) | SIGMAR1DRD2KCNA3KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017079476-A1 | LSD1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2017-05-11 | — | — | WO | disclosed |