SCHEMBL1884535

SCHEMBL1884535

Cn1c(-c2ccccc2)c(C(=O)C=Cc2ccccc2)c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
MAPT P10636 2/20 0.58
HTT P42858 2/20 0.58
ATM Q13315 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
PADI4 Q9UM07 4/20 0.56
HK1 P19367 1/20 0.54
HKDC1 Q2TB90 1/20 0.54
LMNA P02545 2/20 0.50
CYP2C19 P33261 2/20 0.49
HSD17B10 Q99714 1/20 0.49
KMT2A Q03164 3/20 0.48
MEN1 O00255 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7487890 0.79 ALDH1A1 (0.70) ALDH1A1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL7278419 0.78 ALDH1A1 (0.68) ALDH1A1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL12374652 0.77 PADI4 (0.60) ALDH1A1NPC1RAB9AMAPTHTT
SCHEMBL15667319 0.77 ALDH1A1 (0.67) ALDH1A1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL1884536 0.76 ALDH1A1 (0.61) ALDH1A1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL9353411 0.75 ALDH1A1 (0.60) ALDH1A1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL9353665 0.74 ALDH1A1 (0.59) ALDH1A1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL23467988 0.73 PADI4 (0.78) SMN1; SMN2PADI4LMNAKMT2A
SCHEMBL6490375 0.73 ALDH1A1 (0.66) ALDH1A1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL6490384 0.73 ALDH1A1 (0.66) ALDH1A1NPC1RAB9ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7939674-B2 Process for producing an aromatic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-10 US disclosed
US-7700642-B2 Process for producing an aromatic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-20 US disclosed
US-20090111999-A1 PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-30 US disclosed
US-20080221337-A1 Process for Producing an Aromatic Unsaturated Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-11 US disclosed
EP-1666440-A1 METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND Sumitomo Chemical Company, Limited (JP) 2006-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080221337-A1 Process for Producing an Aromatic Unsaturated Compound AHR, AR, ARSA ALDH1A1 231/4885NPC1 1084/4885RAB9A 3395/4885
US-20090111999-A1 PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND AHR, AR, ARSA ALDH1A1 231/4885NPC1 1084/4885RAB9A 3395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.