Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 7/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374862 | 0.89 | PADI4 (0.51) | PADI4NPC1RAB9AKMT2AMAPT | |
| SCHEMBL12374654 | 0.86 | LMNA (0.49) | PADI4NPC1RAB9AKMT2ACYP3A4 | |
| SCHEMBL12374696 | 0.82 | KMT2A (0.52) | PADI4NPC1RAB9AKMT2ACYP3A4 | |
| SCHEMBL29701 | 0.81 | ALDH1A1 (0.59) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL23467988 | 0.77 | PADI4 (0.78) | PADI4KMT2ALMNA | |
| SCHEMBL1884535 | 0.77 | ALDH1A1 (0.58) | PADI4NPC1RAB9AKMT2ACYP3A4 | |
| SCHEMBL14288822 | 0.77 | ALDH1A1 (0.71) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL12374651 | 0.77 | PADI4 (0.65) | PADI4NPC1RAB9AKMT2AMAPT | |
| SCHEMBL23468020 | 0.76 | PADI4 (1.00) | PADI4CYP3A4ABCG2 | |
| SCHEMBL12374650 | 0.76 | KMT2A (0.54) | PADI4NPC1RAB9AKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524729-B2 | Cinnamoyl derivatives and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-09-03 | — | — | US | disclosed |
| US-7989478-B2 | decreases expression of a Type I collage gene in a tissue to induce a reduction in accumulation of collagen and thereby improves tissue fibrosis | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-02 | — | — | US | disclosed |
| US-20070123521-A1 | Cinnamoyl derivatives and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123521-A1 | Cinnamoyl derivatives and use thereof | CES2, EBP, CPT1A | PADI4 2457/4885NPC1 4/4885RAB9A 3002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.