SCHEMBL18845355

SCHEMBL18845355

CCC(C)(I)C(=O)OC1C2CC3CC1CC(O)(C3)C2

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 18/20 0.42
HSD11B2 P80365 1/20 0.38
EPHX2 P34913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5521859 0.86 HSD11B1 (0.44) HSD11B1HSD11B2EPHX2
SCHEMBL19261037 0.84 HSD11B1 (0.46) HSD11B1HSD11B2
SCHEMBL19976016 0.82 HSD11B1 (0.39) HSD11B1EPHX2
SCHEMBL13430021 0.81 HSD11B1 (0.43) HSD11B1HSD11B2EPHX2
SCHEMBL12824509 0.80 HSD11B1 (0.43) HSD11B1HSD11B2EPHX2
SCHEMBL12128673 0.80 HSD11B1 (0.46) HSD11B1HSD11B2
SCHEMBL14527522 0.79 HSD11B1 (0.42) HSD11B1HSD11B2EPHX2
SCHEMBL13553287 0.78 HSD11B1 (0.39) HSD11B1HSD11B2EPHX2
SCHEMBL13081509 0.76 HSD11B1 (0.44) HSD11B1HSD11B2EPHX2
SCHEMBL14732672 0.74 HSD11B1 (0.39) HSD11B1HSD11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9904172-B2 Shrink material and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-02-27 US disclosed
US-9790166-B2 Polymer, monomer, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-10-17 US disclosed
US-9758609-B2 Monomer, polymer, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-09-12 US disclosed
US-9740100-B2 Hemiacetal compound, polymer, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-08-22 US disclosed
US-20170131635-A1 MONOMER, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170131635-A1 MONOMER, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS H1-2, H1-0, H1-4 HSD11B1 2220/4885HSD11B2 3156/4885EPHX2 647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.