SCHEMBL1884663

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1885089	0.86	HDAC1 (1.00)	HDAC1HDAC6HDAC2HDAC3HDAC4
	SCHEMBL1888002	0.81	HDAC1 (0.73)	HDAC1NPC1HDAC6HPGD
	SCHEMBL1884493	0.79	HDAC1 (0.78)	HDAC1HDAC6HDAC2HDAC3HDAC4
	SCHEMBL1889752	0.79	HDAC1 (0.78)	HDAC1HDAC6HDAC2HDAC3HDAC4
	SCHEMBL1883965	0.78	HDAC1 (0.72)	HDAC1HPGD
	SCHEMBL27361080	0.78	TSHR (0.72)	HDAC1TSHRNPC1HDAC6HDAC2
	SCHEMBL3982575	0.77	HDAC1 (0.83)	HDAC1HDAC6HDAC2HDAC3
	SCHEMBL1885050	0.76	HDAC1 (0.76)	HDAC1NPC1HDAC6HDAC2HDAC3
	SCHEMBL8291123	0.76	HDAC1 (1.00)	HDAC1HDAC6HDAC2HDAC3HDAC4
	SCHEMBL1890070	0.76	HDAC1 (0.81)	HDAC1HDAC6HDAC2HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.