Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298780 | 0.78 | — | — | |
| SCHEMBL11076028 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL11687621 | 0.72 | FFAR3 (0.38) | FFAR3ALDH1A1LMNAGLATSHR | |
| SCHEMBL3827023 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL11688363 | 0.69 | CHRM1 (0.43) | FFAR3ALDH1A1LMNAGLATSHR | |
| SCHEMBL31373252 | 0.69 | LMNA (0.48) | FFAR3ALDH1A1ALDH2LMNAGLA | |
| SCHEMBL5759921 | 0.69 | NPC1 (0.35) | FFAR3ALDH1A1ALDH2LMNAGLA | |
| SCHEMBL6831268 | 0.69 | — | — | |
| SCHEMBL10808296 | 0.67 | LMNA (0.33) | FFAR3ALDH1A1LMNAGLATSHR | |
| Hydrochloric Acid SCHEMBL11688808 | 0.67 | LMNA (0.47) | FFAR3ALDH1A1ALDH2LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947709-B2 | Inhibit HIV-1 RT; 3-[6-Bromo-2-fluoro-3-(2-oxo-2,3-dihydro-benzoimidazol-1-ylmethyl)-phenoxy]-5-chloro-benzonitrile for example; AIDS or AIDS-related Complex (ARC) | ROCHE PALO ALTO LLC (US) | 2011-05-24 | — | — | US | disclosed |