SCHEMBL6298780

SCHEMBL6298780

CCN(C(=O)O)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3827023 0.84
SCHEMBL31373252 0.82 LMNA (0.48)
Hydrochloric Acid SCHEMBL11688363 0.82 CHRM1 (0.43)
SCHEMBL5759921 0.82 NPC1 (0.35)
SCHEMBL6831268 0.82
Hydrochloric Acid SCHEMBL11687621 0.80 FFAR3 (0.38)
SCHEMBL10808296 0.80 LMNA (0.33)
Hydrochloric Acid SCHEMBL11688808 0.80 LMNA (0.47)
SCHEMBL1884833 0.78 FFAR3 (0.36)
SCHEMBL11076028 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030209491-A1 Simulated activity of protein a displayed by ligands attached to a cellulose bead surface ACCURATE POLYMERS, LTD. 2003-11-13 US claimed
CN-1436095-A Mimetic Activity of protein A by ligands attached to the surface of cellulose beads ACCURATE POLYMERS INC (US) 2003-08-13 CN claimed
EP-1276557-A2 SIMULATED ACTIVITY OF PROTEIN A DISPLAYED BY LIGANDS ATTACHED TO A CELLULOSE BEAD SURFACE Accurate Polymers, Ltd. (US) 2003-01-22 EP claimed
US-20010045384-A1 Simulated activity of protein a displayed by ligands attached to a cellulose bead surface ACCURATE POLYMERS, LTD. 2001-11-29 US claimed
WO-2001083515-A2 SIMULATED ACTIVITY OF PROTEIN A DISPLAYED BY LIGANDS ATTACHED TO A CELLULOSE BEAD SURFACE ACCURATE POLYMERS, INC. (US) 2001-11-08 WO claimed
US-9028785-B2 High CO2 to amine adsorption capacity CO2 scrubbing processes EXXONMOBIL RESEACH AND ENGINEERING COMPANY (US) 2015-05-12 US disclosed
US-20140038968-A1 AMINO-HETEROARYL-CONTAINING PROKINETICIN 1 RECEPTOR ANTAGONISTS COATS STEVEN J (US) 2014-02-06 US disclosed
US-8372973-B2 Prokineticin 1 receptor antagonists JANSSEN PHARMACEUTICA N.V. (BE) 2013-02-12 US disclosed
US-8362247-B2 Prokineticin 1 receptor antagonists JANSSEN PHARMACEUTICA N.V. (BE) 2013-01-29 US disclosed
US-8324380-B2 Amino-heteroaryl-containing prokineticin 1 receptor antagonists JANSSEN PHARMACEUTICA NV (BE) 2012-12-04 US disclosed
US-20120129862-A1 PROKINETICIN 1 RECEPTOR ANTAGONISTS COATS STEVEN J (US) 2012-05-24 US disclosed
US-20120063979-A1 High CO2 to Amine Adsorption Capacity CO2 Scrubbing Processes EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-03-15 US disclosed
CN-1436095-A Mimetic Activity of protein A by ligands attached to the surface of cellulose beads ACCURATE POLYMERS INC (US) 2003-08-13 CN disclosed
US-6572767-B2 Purification of proteins by complexing to support matrix ACCURATE POLYMERS, LTD. 2003-06-03 US disclosed
EP-1276557-A2 SIMULATED ACTIVITY OF PROTEIN A DISPLAYED BY LIGANDS ATTACHED TO A CELLULOSE BEAD SURFACE Accurate Polymers, Ltd. (US) 2003-01-22 EP disclosed
US-6358984-B1 FOR THERAPY OF HYPERTENSION AND/OR DISEASES SUCH AS HEART AND RENAL DISEASES LEAD CHEMICAL CO., LTD. (JP) 2002-03-19 US disclosed
US-20010045384-A1 Simulated activity of protein a displayed by ligands attached to a cellulose bead surface ACCURATE POLYMERS, LTD. 2001-11-29 US disclosed
WO-2001083515-A2 SIMULATED ACTIVITY OF PROTEIN A DISPLAYED BY LIGANDS ATTACHED TO A CELLULOSE BEAD SURFACE ACCURATE POLYMERS, INC. (US) 2001-11-08 WO disclosed
US-6232335-B1 A BIPHENYL TRIAZOLE COMPOUND USEFUL AS A ANGIOTENSIN II CONVERTING ENZYME INHIBITORS EFFECTIVE IN THE TREATMENT OF HYPERTENSION OR HEART FAILURE LEAD CHEMICAL CO., LTD. (JP) 2001-05-15 US disclosed
EP-0936221-A1 NOVEL 2,4-DIOXOPYRROLIDINE AND 2,4-DIOXOTETRAHYDROFURAN DERIVATIVES AND MEDICINES CONTAINING THE SAME AS THE ACTIVE INGREDIENT LEAD CHEMICAL COMPANY LTD. (JP) 1999-08-18 EP disclosed