Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 18/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26148600 | 0.91 | KDM1A (0.54) | KDM1AALDH1A1L3MBTL1 | |
| SCHEMBL18848747 | 0.90 | KDM1A (0.46) | KDM1AALDH1A1 | |
| SCHEMBL18848758 | 0.87 | KDM1A (0.45) | KDM1AALDH1A1 | |
| SCHEMBL16455123 | 0.84 | PHGDH (0.40) | KDM1AALDH1A1L3MBTL1 | |
| SCHEMBL26148643 | 0.82 | KDM1A (0.55) | KDM1AALDH1A1 | |
| SCHEMBL18848469 | 0.78 | POLB (0.46) | KDM1A | |
| SCHEMBL16455197 | 0.78 | KDM1A (0.48) | KDM1A | |
| SCHEMBL18848609 | 0.77 | KDM1A (0.47) | KDM1A | |
| SCHEMBL16455168 | 0.76 | KDM1A (0.47) | KDM1A | |
| SCHEMBL20781336 | 0.76 | KDM1A (0.65) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017079753-A1 | LYSINE-SPECIFIC HISTONE DEMETHYLASE AS A NOVEL THERAPEUTIC TARGET IN MYELOPROLIFERATIVE NEOPLASMS | IMAGO BIOSCIENCES, INC. (US) | 2017-05-11 | — | — | WO | disclosed |