Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18848613 | 0.90 | KDM1A (0.46) | KDM1AALDH1A1 | |
| SCHEMBL18848469 | 0.89 | POLB (0.46) | KDM1APOLB | |
| SCHEMBL16455162 | 0.79 | MMP8 (0.40) | ALDH1A1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL18848617 | 0.77 | KDM1A (0.63) | KDM1AALDH1A1TGM2 | |
| SCHEMBL18848758 | 0.76 | KDM1A (0.45) | KDM1AALDH1A1POLB | |
| SCHEMBL16455183 | 0.76 | KDM1A (0.64) | KDM1AALDH1A1TGM2 | |
| SCHEMBL16455067 | 0.75 | HPGD (0.47) | ALDH1A1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL16455069 | 0.75 | KDM1A (0.51) | KDM1A | |
| SCHEMBL16455031 | 0.72 | NPC1 (0.47) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL20545683 | 0.72 | KDM1A (0.62) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017079753-A1 | LYSINE-SPECIFIC HISTONE DEMETHYLASE AS A NOVEL THERAPEUTIC TARGET IN MYELOPROLIFERATIVE NEOPLASMS | IMAGO BIOSCIENCES, INC. (US) | 2017-05-11 | — | — | WO | disclosed |