Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 8/20 | 0.35 |
| ▸ | MTTP | P55157 | 4/20 | 0.35 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18059491 | 0.79 | KDM1A (0.39) | UGCGMTTPKDM1AMEN1HPGD | |
| SCHEMBL19466139 | 0.79 | KDM1A (0.39) | UGCGMTTPKDM1AMEN1HPGD | |
| SCHEMBL23591855 | 0.75 | KDM1A (0.35) | UGCGMTTPKDM1ATACR1CYP3A4 | |
| SCHEMBL16455121 | 0.72 | MEN1 (0.46) | UGCGMTTPKDM1ATACR1CYP3A4 | |
| SCHEMBL18059507 | 0.71 | KDM1A (0.46) | KDM1AKMT2A | |
| SCHEMBL18848608 | 0.71 | KDM1A (0.46) | KDM1AKMT2A | |
| SCHEMBL18848473 | 0.68 | KDM1A (0.49) | KDM1ACYP3A4HPGDKMT2A | |
| SCHEMBL18059520 | 0.68 | KDM1A (0.49) | KDM1ACYP3A4HPGDKMT2A | |
| SCHEMBL18059490 | 0.68 | KDM1A (0.44) | KDM1AKMT2A | |
| SCHEMBL18848438 | 0.68 | KDM1A (0.44) | KDM1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017079753-A1 | LYSINE-SPECIFIC HISTONE DEMETHYLASE AS A NOVEL THERAPEUTIC TARGET IN MYELOPROLIFERATIVE NEOPLASMS | IMAGO BIOSCIENCES, INC. (US) | 2017-05-11 | — | — | WO | disclosed |