Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.51 |
| ▸ | PREP | P48147 | 5/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | FAP | Q12884 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | F9 | P00740 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672214 | 0.78 | PREP (0.58) | PREPDPP4FAPDPP8DPP9 | |
| SCHEMBL18848460 | 0.77 | KDM1A (0.52) | KDM1AF9 | |
| SCHEMBL18848602 | 0.76 | KDM1A (0.51) | KDM1AF9 | |
| SCHEMBL5673598 | 0.76 | L3MBTL1 (0.55) | PREPDPP4 | |
| SCHEMBL18848701 | 0.74 | KDM1A (0.50) | KDM1AF9 | |
| SCHEMBL18848727 | 0.74 | KDM1A (0.51) | KDM1AF9 | |
| SCHEMBL18848589 | 0.72 | KDM1A (0.51) | KDM1AF9 | |
| SCHEMBL5672334 | 0.70 | KMT2A (0.50) | PREPDPP4FAP | |
| SCHEMBL5672207 | 0.68 | PREP (0.65) | PREP | |
| SCHEMBL5673611 | 0.68 | CHRM1 (0.47) | PREPFAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017079753-A1 | LYSINE-SPECIFIC HISTONE DEMETHYLASE AS A NOVEL THERAPEUTIC TARGET IN MYELOPROLIFERATIVE NEOPLASMS | IMAGO BIOSCIENCES, INC. (US) | 2017-05-11 | — | — | WO | disclosed |