Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 3/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.42 |
| ▸ | CTSC | P53634 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SDCBP | O00560 | 1/20 | 0.39 |
| ▸ | SDC2 | P34741 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | NCF1 | P14598 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PRF1 | P14222 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17208003 | 0.87 | DDB1 (0.46) | DDB1CRBNCTSCCTSKSDCBP | |
| SCHEMBL7904241 | 0.82 | HTR2A (0.47) | DDB1CRBNCTSCCTSKSDCBP | |
| SCHEMBL29289728 | 0.81 | DDB1 (0.44) | DDB1CRBNCTSCCTSKSDCBP | |
| SCHEMBL23981898 | 0.81 | DDB1 (0.44) | DDB1CRBNCTSCCTSKSDCBP | |
| SCHEMBL24221625 | 0.78 | SDCBP (0.43) | DDB1CRBNCTSCCTSKSDCBP | |
| SCHEMBL25060995 | 0.78 | DDB1 (0.42) | DDB1CRBNCTSCCTSKSDCBP | |
| SCHEMBL14566645 | 0.76 | DDB1 (0.54) | DDB1CRBNSDCBPSDC2HDAC8 | |
| SCHEMBL23349346 | 0.75 | KMT2A (0.51) | HDAC8HDAC1HDAC6 | |
| SCHEMBL31098599 | 0.74 | DDB1 (0.39) | DDB1CRBNCTSCCTSKSDCBP | |
| SCHEMBL29289681 | 0.74 | DDB1 (0.39) | DDB1CRBNCTSCCTSKSDCBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017076852-A1 | INDOLIN-2-ONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2017-05-11 | — | — | WO | disclosed |