SCHEMBL23349346

SCHEMBL23349346

CN1Cc2ccc(CN3C(=O)c4ccccc4C3=O)cc2C1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.51
PKM P14618 1/20 0.51
TSHR P16473 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
PABPC1 P11940 1/20 0.51
ALOX15 P16050 1/20 0.51
MAPK1 P28482 1/20 0.51
HPGD P15428 2/20 0.48
MAPT P10636 1/20 0.48
HTT P42858 1/20 0.48
ADRA1D P25100 3/20 0.46
ADRA1A P35348 3/20 0.46
ADRA1B P35368 3/20 0.46
CASP3 P42574 3/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17208003 0.80 DDB1 (0.46) KMT2A
SCHEMBL7904241 0.79 HTR2A (0.47) KMT2ASMN1; SMN2MAPK1HPGDMAPT
SCHEMBL29289728 0.77 DDB1 (0.44) KMT2AHPGD
SCHEMBL23981898 0.77 DDB1 (0.44) KMT2APKMHPGDMAPTHTT
SCHEMBL25060995 0.75 DDB1 (0.42) KMT2AALOX15HDAC1HDAC8HDAC6
SCHEMBL24221625 0.75 SDCBP (0.43) KMT2AALOX15MAPTUSP1POLB
SCHEMBL18848849 0.75 DDB1 (0.42) HDAC1HDAC8HDAC6
SCHEMBL29455643 0.74 KMT2A (0.63) KMT2APKMTSHRSMN1; SMN2ALOX15
SCHEMBL470341 0.74 KMT2A (0.63) KMT2APKMTSHRSMN1; SMN2ALOX15
SCHEMBL2258501 0.72 KMT2A (0.70) KMT2APKMTSHRSMN1; SMN2PABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210139616-A1 Photopolymerization Synergist Piedmont Chemical Industries, LLC 2021-05-13 US disclosed