SCHEMBL1885017

SCHEMBL1885017

[CH2][C@H](CNC(=O)OCOC(=O)C(C)C)c1ccc(Cl)cc1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.40
L3MBTL1 Q9Y468 4/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
RAB9A P51151 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
NPC1 O15118 2/20 0.36
ALDH1A1 P00352 2/20 0.35
FFAR2 O15552 1/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 1/20 0.35
LMNA P02545 1/20 0.34
ALOX12 P18054 1/20 0.34
KCNH2 Q12809 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1884874 1.00 MAPT (0.40) MAPTL3MBTL1SMN1; SMN2RAB9AMEN1
SCHEMBL1888752 0.85 L3MBTL1 (0.41) MAPTL3MBTL1SMN1; SMN2RAB9AMEN1
SCHEMBL1884816 0.85 MAPT (0.36) MAPTL3MBTL1SMN1; SMN2RAB9AMEN1
SCHEMBL1884157 0.85 L3MBTL1 (0.41) MAPTL3MBTL1SMN1; SMN2RAB9AMEN1
SCHEMBL1884547 0.85 MAPT (0.36) MAPTL3MBTL1SMN1; SMN2RAB9AMEN1
SCHEMBL1884906 0.83 MAPT (0.42) MAPTL3MBTL1SMN1; SMN2RAB9AMEN1
SCHEMBL1891741 0.83 MAPT (0.42) MAPTL3MBTL1SMN1; SMN2RAB9AMEN1
SCHEMBL1888802 0.82 MAPT (0.41) MAPTL3MBTL1SMN1; SMN2RAB9AMEN1
SCHEMBL1886204 0.82 MAPT (0.41) MAPTL3MBTL1SMN1; SMN2RAB9AMEN1
SCHEMBL1884778 0.82 MAPT (0.41) MAPTL3MBTL1SMN1; SMN2RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150030937-A1 Nonaqueous Electrolyte for Lithium Ion and Lithium Metal Batteries ENERIZE CORPORATION (US) 2015-01-29 US claimed
US-20150030937-A1 Nonaqueous Electrolyte for Lithium Ion and Lithium Metal Batteries ENERIZE CORPORATION (US) 2015-01-29 US disclosed
US-20110104574-A1 Nonaqueous electrolyte for lithium Ion and lithium metal batteries ENERIZE CORPORATION (US) 2011-05-05 US disclosed
US-7494985-B2 Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use XENOPORT, INC. (US) 2009-02-24 US disclosed
US-20060111325-A1 Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use XENOPORT, INC. 2006-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060111325-A1 Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use APEH, AASDHPPT, AGPS MAPT 4107/4885L3MBTL1 2410/4885SMN1; SMN2 900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.