Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468217 | 0.80 | NOS3 (0.38) | SKP2CA2ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL28166642 | 0.80 | KAT8 (0.56) | KAT8PPARAALDH1A1ESR1ADRA2A | |
| SCHEMBL16404803 | 0.79 | TAAR1 (0.42) | HTR2AALDH1A1ADRA2ASLC6A2SLC6A3 | |
| SCHEMBL10752071 | 0.78 | SKP2 (0.63) | SKP2HTR2ACA2ALDH1A1ESR1 | |
| SCHEMBL15175048 | 0.77 | SKP2 (0.58) | SKP2HTR2ACA2KAT8PPARA | |
| SCHEMBL25433778 | 0.77 | SKP2 (0.61) | SKP2HTR2AKAT8PPARAALDH1A1 | |
| SCHEMBL11322552 | 0.77 | SKP2 (0.61) | SKP2HTR2AKAT8PPARAALDH1A1 | |
| SCHEMBL6348569 | 0.77 | SKP2 (0.61) | SKP2HTR2AKAT8PPARAALDH1A1 | |
| SCHEMBL7204038 | 0.77 | SKP2 (0.61) | SKP2HTR2AKAT8PPARAALDH1A1 | |
| SCHEMBL13062022 | 0.76 | CDK1 (0.47) | KAT8PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017077307-A1 | THERAPY AND PHARMACEUTICAL COMPOSITION | UNIVERSITY OF SOUTHAMPTON (GB) | 2017-05-11 | — | — | WO | disclosed |