Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 8/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 8/20 | 0.54 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.54 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18850919 | 1.00 | PSMB8 (0.54) | PSMB8PSMB5PSMB9SMYD3ACHE | |
| SCHEMBL19691215 | 0.91 | SMYD3 (0.57) | PSMB8PSMB5PSMB9SMYD3HDAC3 | |
| SCHEMBL21789270 | 0.85 | SMYD3 (0.68) | PSMB8PSMB5PSMB9SMYD3HDAC3 | |
| SCHEMBL30999011 | 0.84 | SMYD3 (0.48) | PSMB8PSMB5PSMB9SMYD3HDAC3 | |
| SCHEMBL71503 | 0.83 | PSMB8 (0.53) | PSMB8PSMB5PSMB9SMYD3ACHE | |
| SCHEMBL29592982 | 0.80 | SMYD3 (0.43) | PSMB8PSMB5PSMB9SMYD3HDAC3 | |
| SCHEMBL24785692 | 0.78 | PSMB8 (0.51) | PSMB8PSMB5PSMB9SMYD3ACHE | |
| SCHEMBL892462 | 0.76 | PSMB8 (0.54) | PSMB8PSMB5PSMB9 | |
| SCHEMBL70303 | 0.75 | SMYD3 (0.55) | PSMB8PSMB5PSMB9SMYD3HDAC3 | |
| SCHEMBL24784759 | 0.74 | PSMB8 (0.52) | PSMB8PSMB5PSMB9SMYD3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11678659-B2 | Use as rodenticides of compounds that inhibit blood coagulation | GULBA DIETRICH (DE) | 2023-06-20 | — | — | US | disclosed |
| US-20170127667-A1 | USE AS RODENTICIDES OF COMPOUNDS THAT INHIBIT BLOOD COAGULATION | GULBA DIETRICH (DE) | 2017-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11678659-B2 | Use as rodenticides of compounds that inhibit blood coagulation | PLAT, F2R, PLAUR | PSMB8 2178/4885PSMB5 1781/4885PSMB9 1489/4885 |
| US-20170127667-A1 | USE AS RODENTICIDES OF COMPOUNDS THAT INHIBIT BLOOD COAGULATION | PLAT, F2R, PLAUR | PSMB8 2178/4885PSMB5 1781/4885PSMB9 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.