SCHEMBL1885137

SCHEMBL1885137

O=P(O)(F)OCC1CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.43
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP3 P08254 1/20 0.40
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40
CA9 Q16790 1/20 0.40
LMNA P02545 1/20 0.39
METAP1 P53582 1/20 0.39
SLC1A3 P43003 3/20 0.36
SLC1A2 P43004 3/20 0.36
SLC1A1 P43005 3/20 0.36
PARP10 Q53GL7 3/20 0.34
PARP15 Q460N3 2/20 0.34
CTSL P07711 1/20 0.32
CTSB P07858 1/20 0.32
CTSK P43235 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6026930 0.83 SRC (0.45) SRCCA12CA1CA2MMP1
SCHEMBL27276638 0.81 SRC (0.44) SRCCA12CA1CA2MMP1
SCHEMBL3429348 0.80 FBP1 (0.43) SRCCA12CA1CA2MMP1
SCHEMBL23884945 0.79 SRC (0.43) SRCCA12CA1CA2MMP1
SCHEMBL779866 0.79 SRC (0.43) SRCCA12CA1CA2MMP1
SCHEMBL779144 0.78 SRC (0.38) SRCCA12CA1CA2MMP1
SCHEMBL11434998 0.78 SRC (0.41) SRCCA12CA1CA2MMP1
SCHEMBL777334 0.78 SRC (0.42) SRCCA12CA1CA2MMP1
SCHEMBL777568 0.78 SRC (0.42) SRCCA12CA1CA2MMP1
SCHEMBL779199 0.77 SRC (0.41) SRCCA12CA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8245564-B1 Chemical sample collection and detection system NORTHROP GRUMMAN SYSTEMS CORPORATION (US) 2012-08-21 US disclosed
US-20120198912-A1 CHEMICAL SAMPLE COLLECTION AND DETECTION SYSTEM NORTHROP GRUMMAN SYSTEMS CORPORATION 2012-08-09 US disclosed
US-8218146-B2 System and method for detecting a target substance NORTHROP GRUMMAN SYSTEMS CORPORATION (US) 2012-07-10 US disclosed
US-20120120392-A1 Non-traditional agent/dusty agent detection system NORTHROP GRUMMAN SYSTEMS CORPORATION 2012-05-17 US disclosed
WO-2011078880-A2 SOLUTION ANALYSIS USING ATMOSPHERIC PRESSURE IONIZATION TECHNIQUES NORTHROP GRUMMAN SYSTEMS CORPORATION (US) 2011-06-30 WO disclosed
US-20110108724-A1 Apparatus, System and Method for Purifying Nucleic Acids EWING KENNETH J 2011-05-12 US disclosed
US-20100208267-A1 System and method for detecting a target substance NORTHROP GRUMMAN SYSTEMS CORPORATION 2010-08-19 US disclosed
US-20100096546-A1 Solution Analysis Using Atmospheric Pressure Ionization Techniques NORTHROP GRUMMAN SYSTEMS CORPORATION (US) 2010-04-22 US disclosed
WO-2010008450-A2 CHEMICAL SAMPLE COLLECTION AND DETECTION USING ATMOSPHERIC PRESSURE IONIZATION NORTHROP GRUMMAN SYSTEMS CORPORATION (US) 2010-01-21 WO disclosed
US-20090317916-A1 Chemical sample collection and detection device using atmospheric pressure ionization NORTHROP GRUMMAN SYSTEMS CORPORATION 2009-12-24 US disclosed
EP-0672169-A1 BIOSENSOR FOR DETECTION OF AND DISTINGUISHING BETWEEN CHOLINESTERASES INHIBITORS ORITEST S. S R.O. (CZ) 1995-09-20 EP disclosed
WO-1994005808-A1 BIOSENSOR FOR DETECTION OF AND DISTINGUISHING BETWEEN CHOLINESTERASES INHIBITORS ORITEST S. S R.O. (CZ) 1994-03-17 WO disclosed