Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27276638 | 0.98 | SRC (0.44) | SRCCA12CA1CA2MMP1 | |
| SCHEMBL3429348 | 0.98 | FBP1 (0.43) | SRCCA12CA1CA2MMP1 | |
| SCHEMBL11520489 | 0.88 | — | — | |
| SCHEMBL23884945 | 0.83 | SRC (0.43) | SRCCA12CA1CA2MMP1 | |
| SCHEMBL779866 | 0.83 | SRC (0.43) | SRCCA12CA1CA2MMP1 | |
| SCHEMBL1885137 | 0.83 | SRC (0.43) | SRCCA12CA1CA2MMP1 | |
| SCHEMBL11434998 | 0.81 | SRC (0.41) | SRCCA12CA1CA2MMP1 | |
| SCHEMBL777334 | 0.81 | SRC (0.42) | SRCCA12CA1CA2MMP1 | |
| SCHEMBL777568 | 0.81 | SRC (0.42) | SRCCA12CA1CA2MMP1 | |
| SCHEMBL779199 | 0.80 | SRC (0.41) | SRCCA12CA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1148374-C | Phosphorous alicyclic epoxy compound and its prepn | 中国科学院化学研究所 | 2004-05-05 | — | — | CN | claimed |
| CN-1403465-A | Phosphorous alicyclic epoxy compound and its prepn | CHINESE ACAD INST CHEMISTRY (CN) | 2003-03-19 | — | — | CN | claimed |
| EP-1644361-A1 | CHINAZOLINE DERIVATIVES AS AURORA KINASE INHIBITORS | Astrazeneca AB (SE) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004113324-A1 | CHINAZOLINE DERIVATIVES AS AURORA KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-12-29 | — | — | WO | disclosed |
| CN-1148374-C | Phosphorous alicyclic epoxy compound and its prepn | 中国科学院化学研究所 | 2004-05-05 | — | — | CN | disclosed |
| CN-1459454-A | Preparation method of phosphorus containing trifunctional group liquid alicyclic epoxide compound | CHINESE ACAD INST CHEMISTRY (CN) | 2003-12-03 | — | — | CN | disclosed |
| CN-1403465-A | Phosphorous alicyclic epoxy compound and its prepn | CHINESE ACAD INST CHEMISTRY (CN) | 2003-03-19 | — | — | CN | disclosed |
| CN-1096285-A | Thermal cracking process with reduced coking | AMOCO CORP (US) | 1994-12-14 | — | — | CN | disclosed |
| CN-1015059-B | The preparation method of isoquinilone derivatives | GLAXO GROUP LTD (GB) | 1991-12-11 | — | — | CN | disclosed |
| CN-87105778-A | Isoquinilone derivatives | — | 1988-02-24 | — | — | CN | disclosed |
| US-4181785-A | ADDITION POLYMER FROM EPOXY MONOMER AND HYDROXY MONOMER, ALKYL PHOSPHATE | FORD MOTOR COMPANY (US) | 1980-01-01 | — | — | US | disclosed |
| US-4181784-A | ADDITION POLYMER FROM EPOXY MONOMER, ALKYL PHOSPHATE | FORD MOTOR COMPANY (US) | 1980-01-01 | — | — | US | disclosed |