⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1803079 | 0.80 | — | — | |
| SCHEMBL31655498 | 0.78 | — | — | |
| SCHEMBL27834410 | 0.70 | — | — | |
| SCHEMBL2852458 | 0.67 | — | — | |
| SCHEMBL440610 | 0.64 | — | — | |
| SCHEMBL17608785 | 0.64 | — | — | |
| SCHEMBL28257312 | 0.61 | — | — | |
| SCHEMBL585497 | 0.59 | — | — | |
| SCHEMBL6286747 | 0.59 | — | — | |
| SCHEMBL2973243 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131861-A2 | 2-Substituted-3-sulfonamidepyridine compounds, process for preparing and pharmaceutical compositions comprising the same | FABRICA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS ABELLO, S.A. (ES) | 1985-01-23 | — | — | EP | claimed |
| US-20240150365-A1 | PYRIDINYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | HOTSPOT THERAPEUTICS, INC. | 2024-05-09 | — | — | US | disclosed |
| WO-2024044344-A1 | PYRIDINYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | HOTSPOT THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| CN-101522651-B | Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents | HOFFMANN LA ROCHE | 2011-11-16 | — | — | CN | disclosed |
| US-7939532-B2 | Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents | HOFFMANN-LA ROCHE INC. (US) | 2011-05-10 | — | — | US | disclosed |
| US-20100292247-A1 | HETEROCYCLYL PYRIDYL SULFONAMIDE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-11-18 | — | — | US | disclosed |
| CN-101522651-A | Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 2009-09-02 | — | — | CN | disclosed |
| EP-2079719-A1 | HETEROCYCLYL PYRIDYL SULFONAMIDE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008049605-A1 | HETEROCYCLYL PYRIDYL SULFONAMIDE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-05-02 | — | — | WO | disclosed |