Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18852198 | 0.85 | KMT2A (0.38) | MAPTKMT2APOLBMEN1SMN1; SMN2 | |
| SCHEMBL18852142 | 0.83 | HPGD (0.41) | MAPTKMT2APOLBMEN1SMN1; SMN2 | |
| SCHEMBL18852197 | 0.83 | MAPT (0.36) | MAPTKMT2APOLBMEN1SMN1; SMN2 | |
| SCHEMBL18852210 | 0.82 | MAPT (0.37) | MAPTKMT2APOLBMEN1SMN1; SMN2 | |
| SCHEMBL18852000 | 0.81 | MAPT (0.36) | MAPTKMT2APOLBMEN1SMN1; SMN2 | |
| SCHEMBL18852073 | 0.80 | MAPT (0.38) | MAPTKMT2APOLBMEN1SMN1; SMN2 | |
| SCHEMBL18852204 | 0.79 | MEN1 (0.35) | MAPTKMT2APOLBMEN1SMN1; SMN2 | |
| SCHEMBL18852215 | 0.78 | KDM4E (0.34) | MAPTKMT2APOLBMEN1SMN1; SMN2 | |
| SCHEMBL16275615 | 0.78 | ALOX5 (0.35) | MAPTKMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL17405533 | 0.78 | KEAP1 (0.37) | MAPTKMT2AMEN1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017078182-A1 | BENZIMIDAZOLE FUSED HETEROARYLS | IDEMITSU KOSAN CO., LTD. (JP) | 2017-05-11 | — | — | WO | disclosed |