Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19007621 | 0.89 | P2RX7 (0.43) | P2RX7NISCHNPC1MEN1KMT2A | |
| SCHEMBL18852008 | 0.84 | P2RX7 (0.39) | P2RX7NPC1MEN1KMT2AHPGD | |
| SCHEMBL18904926 | 0.84 | P2RX7 (0.37) | P2RX7NPC1MEN1KMT2AHPGD | |
| SCHEMBL17851200 | 0.83 | P2RX7 (0.40) | P2RX7NISCHNPC1MEN1KMT2A | |
| SCHEMBL18253718 | 0.83 | P2RX7 (0.38) | P2RX7NPC1MEN1KMT2AHPGD | |
| SCHEMBL18885397 | 0.83 | P2RX7 (0.50) | P2RX7NISCHNPC1MEN1KMT2A | |
| SCHEMBL18561425 | 0.82 | P2RX7 (0.39) | P2RX7NISCHNPC1MEN1KMT2A | |
| SCHEMBL15690774 | 0.81 | MEN1 (0.41) | P2RX7NPC1MEN1KMT2AHPGD | |
| SCHEMBL18977534 | 0.81 | P2RX7 (0.41) | P2RX7NPC1MEN1KMT2AHPGD | |
| SCHEMBL18561430 | 0.81 | P2RX7 (0.41) | P2RX7NISCHNPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017078182-A1 | BENZIMIDAZOLE FUSED HETEROARYLS | IDEMITSU KOSAN CO., LTD. (JP) | 2017-05-11 | — | — | WO | disclosed |