Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15690774 | 0.95 | MEN1 (0.41) | P2RX7MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL19446585 | 0.92 | MEN1 (0.37) | P2RX7MEN1KMT2APOLBGABRA1 | |
| SCHEMBL19007621 | 0.89 | P2RX7 (0.43) | P2RX7MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL15749799 | 0.86 | ALDH1A1 (0.39) | P2RX7MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL18935227 | 0.85 | P2RX7 (0.42) | P2RX7MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL18852242 | 0.84 | P2RX7 (0.39) | P2RX7MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL18767668 | 0.83 | P2RX7 (0.43) | P2RX7MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL17851200 | 0.83 | P2RX7 (0.40) | P2RX7MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL18253718 | 0.83 | P2RX7 (0.38) | P2RX7MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL18885397 | 0.83 | P2RX7 (0.50) | P2RX7MEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017078182-A1 | BENZIMIDAZOLE FUSED HETEROARYLS | IDEMITSU KOSAN CO., LTD. (JP) | 2017-05-11 | — | — | WO | disclosed |