Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | KAT2B | Q92831 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13168998 | 0.89 | MAPT (0.61) | MAPTKDM4EALDH1A1POLBPRSS1 | |
| SCHEMBL2228171 | 0.86 | KAT2B (0.64) | MAPTKDM4EKAT2BALDH1A1POLB | |
| SCHEMBL4557828 | 0.86 | KAT2B (0.64) | MAPTKDM4EKAT2BALDH1A1POLB | |
| SCHEMBL17923845 | 0.86 | KAT2B (0.64) | MAPTKDM4EKAT2BALDH1A1POLB | |
| SCHEMBL30413993 | 0.86 | KAT2B (0.64) | MAPTKDM4EKAT2BALDH1A1POLB | |
| SCHEMBL10622798 | 0.86 | KAT2B (0.72) | MAPTKDM4EKAT2BALDH1A1POLB | |
| SCHEMBL17875231 | 0.85 | MAPT (0.56) | MAPTKDM4EALDH1A1POLBPRSS1 | |
| SCHEMBL10932609 | 0.85 | MAPT (0.63) | MAPTKDM4EKAT2BALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL4699216 | 0.84 | KAT2B (0.65) | MAPTKDM4EKAT2BALDH1A1POLB | |
| SCHEMBL2228520 | 0.84 | KAT2B (0.66) | MAPTKDM4EKAT2BALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198230-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2012-06-12 | — | — | US | disclosed |
| US-20110236344-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2011-09-29 | — | — | US | disclosed |
| US-7956029-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2011-06-07 | — | — | US | disclosed |
| US-7956029-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2011-06-07 | — | — | US | disclosed |
| US-7947647-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947647-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947647-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2011-05-24 | — | — | US | disclosed |
| WO-2010071772-A2 | SYNTHESIS OF 3B-AMINO-5-CHOLESTENE AND RELATED 3B-HALIDES INVOLVING I-STEROID AND RETRO-I-STEROID REARRANGEMENTS | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010071772-A2 | SYNTHESIS OF 3B-AMINO-5-CHOLESTENE AND RELATED 3B-HALIDES INVOLVING I-STEROID AND RETRO-I-STEROID REARRANGEMENTS | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-06-24 | — | — | WO | disclosed |
| US-20100160657-A1 | SYNTHETIC MIMICS OF MAMMALIAN CELL SURFACE RECEPTORS: METHOD AND COMPOSITIONS | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100160657-A1 | SYNTHETIC MIMICS OF MAMMALIAN CELL SURFACE RECEPTORS: METHOD AND COMPOSITIONS | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100160657-A1 | SYNTHETIC MIMICS OF MAMMALIAN CELL SURFACE RECEPTORS: METHOD AND COMPOSITIONS | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100029906-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-02-04 | — | — | US | disclosed |
| US-20100029906-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-02-04 | — | — | US | disclosed |
| US-20090197848-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2009-08-06 | — | — | US | disclosed |
| US-20090197848-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2009-08-06 | — | — | US | disclosed |
| US-20090197848-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2009-08-06 | — | — | US | disclosed |
| US-7514400-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2009-04-07 | — | — | US | disclosed |
| US-7514400-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2009-04-07 | — | — | US | disclosed |
| US-20060229235-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2006-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160657-A1 | SYNTHETIC MIMICS OF MAMMALIAN CELL SURFACE RECEPTORS: METHOD AND COMPOSITIONS | NR1H4, LDLR, NR1H3 | MAPT 4790/4885KDM4E 4505/4885KAT2B 4769/4885 |
| US-20090197848-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | MSR1, M6PR, ASGR1 | MAPT 4740/4885KDM4E 4618/4885KAT2B 4743/4885 |
| US-20060229235-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | MSR1, M6PR, ASGR1 | MAPT 4740/4885KDM4E 4618/4885KAT2B 4743/4885 |
| US-20100029906-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | MSR1, M6PR, ASGR1 | MAPT 4740/4885KDM4E 4618/4885KAT2B 4743/4885 |
| US-20110236344-A1 | Synthetic mimics of mammalian cell surface receptors: method and compositions | MSR1, M6PR, ASGR1 | MAPT 4740/4885KDM4E 4618/4885KAT2B 4743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.