Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37830 | 0.88 | MAPT (0.63) | MAPTKDM4EALDH1A1POLBHCAR3 | |
| SCHEMBL29928397 | 0.88 | MAPT (0.63) | MAPTKDM4EALDH1A1POLBHCAR3 | |
| SCHEMBL4295085 | 0.88 | MAPT (0.63) | MAPTKDM4EALDH1A1POLBHCAR3 | |
| SCHEMBL9755054 | 0.87 | MAPT (0.65) | MAPTKDM4EALDH1A1POLBHCAR3 | |
| SCHEMBL1885233 | 0.85 | MAPT (0.55) | MAPTKDM4EALDH1A1POLBPKM | |
| SCHEMBL13168998 | 0.85 | MAPT (0.61) | MAPTKDM4EALDH1A1POLBHCAR3 | |
| SCHEMBL10932609 | 0.83 | MAPT (0.63) | MAPTKDM4EALDH1A1POLBHCAR3 | |
| SCHEMBL4301793 | 0.83 | MAPT (0.70) | MAPTKDM4EALDH1A1POLBHCAR3 | |
| SCHEMBL1700521 | 0.81 | ALDH1A1 (0.55) | MAPTKDM4EALDH1A1POLBHCAR3 | |
| SCHEMBL1700523 | 0.81 | ALDH1A1 (0.55) | MAPTKDM4EALDH1A1POLBHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566335-B1 | CONTROLLED RELEASE OF ACTIVE COMPOUNDS FROM MACROMOLECULAR CONJUGATES | PROLYNX LLC (US) | 2016-06-29 | — | — | EP | disclosed |