Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 14/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.53 |
| ▸ | HPN | P05981 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5574398 | 0.84 | VCAM1 (0.61) | VCAM1ALOX15HPNMAPTSIRT5 | |
| SCHEMBL12042584 | 0.82 | ALOX15 (0.68) | VCAM1ALOX15HPNMAPTSIRT5 | |
| SCHEMBL18853854 | 0.80 | VCAM1 (0.53) | VCAM1ALOX15HPNMAPTSIRT5 | |
| SCHEMBL5574203 | 0.78 | VCAM1 (0.58) | VCAM1ALOX15HPNMAPTSIRT5 | |
| SCHEMBL13609380 | 0.78 | VCAM1 (0.63) | VCAM1ALOX15HPNMAPTSIRT5 | |
| Camobucol SCHEMBL4734553 | 0.78 | VCAM1 (0.70) | VCAM1ALOX15HPNMAPTSIRT5 | |
| SCHEMBL14586316 | 0.77 | VCAM1 (0.55) | VCAM1ALOX15HPNMAPTSIRT5 | |
| SCHEMBL14598550 | 0.76 | ALOX15 (0.54) | VCAM1ALOX15HPNMAPTSIRT5 | |
| SCHEMBL12042598 | 0.76 | ALOX15 (0.62) | VCAM1ALOX15HPNMAPTSIRT5 | |
| SCHEMBL14037559 | 0.75 | VCAM1 (0.70) | VCAM1ALOX15HPNMAPTSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650332-B1 | Prodrug of probucol and method for preparing the same | WUHAN ZHONG YU YUMIN PHARMACEUTICAL TECHNOLOGY CO. LTD (CN) | 2017-05-16 | — | — | US | disclosed |
| US-9650332-B1 | Prodrug of probucol and method for preparing the same | WUHAN ZHONG YU YUMIN PHARMACEUTICAL TECHNOLOGY CO. LTD (CN) | 2017-05-16 | — | — | US | disclosed |