Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 5/20 | 0.55 |
| ▸ | REN | P00797 | 3/20 | 0.54 |
| ▸ | NMBR | P28336 | 3/20 | 0.53 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | IL1RN | P18510 | 1/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18862442 | 0.94 | GHSR (0.56) | GHSRRENNMBREDNRAERAP2 | |
| SCHEMBL18854334 | 0.88 | GHSR (0.56) | GHSRRENNMBRIL1RNERAP2 | |
| SCHEMBL18854271 | 0.88 | GHSR (0.56) | GHSRRENNMBRIL1RNERAP2 | |
| SCHEMBL18854326 | 0.88 | GHSR (0.56) | GHSRRENNMBRIL1RNERAP2 | |
| SCHEMBL18854269 | 0.85 | GHSR (0.60) | GHSRREN | |
| SCHEMBL18862334 | 0.84 | GHSR (0.57) | GHSRRENNMBRERAP2 | |
| SCHEMBL18862366 | 0.83 | GHSR (0.60) | GHSRRENNMBR | |
| SCHEMBL18854322 | 0.83 | IL23R (0.60) | GHSRREN | |
| SCHEMBL22722178 | 0.83 | GHSR (0.65) | GHSRRENNMBR | |
| SCHEMBL18854323 | 0.83 | GHSR (0.59) | GHSRREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137801-A1 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-05-18 | — | — | US | disclosed |