Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CD69 | Q07108 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12899987 | 0.95 | ALDH1A1 (0.37) | ALDH1A1THRBMAPK1CA1CA2 | |
| SCHEMBL24453797 | 0.89 | ALDH1A1 (0.35) | ALDH1A1THRBMAPK1CA1CA2 | |
| SCHEMBL9914010 | 0.85 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CA1CA2 | |
| SCHEMBL20626631 | 0.85 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CA1CA2 | |
| SCHEMBL16076955 | 0.85 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CA1CA2 | |
| SCHEMBL12337162 | 0.85 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CA1CA2 | |
| SCHEMBL13541601 | 0.85 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CA1CA2 | |
| SCHEMBL12733141 | 0.85 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CA1CA2 | |
| SCHEMBL15616403 | 0.85 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CA1CA2 | |
| SCHEMBL13498558 | 0.85 | ALDH1A1 (0.56) | ALDH1A1THRBMAPK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137801-A1 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-05-18 | — | — | US | disclosed |