SCHEMBL9914010

SCHEMBL9914010

CC(=O)NC1[C@H](C)OC(CO)[C@@H](O)[C@@H]1O

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.56
▸ THRB P10828 1/20 0.56
▸ MAPK1 P28482 2/20 0.53
▸ CD69 Q07108 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ CYP2D6 P10635 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ PYGB P11216 2/20 0.45
▸ GAA P10253 1/20 0.45
▸ CA1 P00915 1/20 0.44
▸ CA2 P00918 1/20 0.44
▸ CA9 Q16790 1/20 0.44
▸ OGA O60502 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14823585 1.00 ALDH1A1 (0.56) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL13541601 1.00 ALDH1A1 (0.56) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL12295742 1.00 ALDH1A1 (0.56) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL15616403 1.00 ALDH1A1 (0.56) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL12733141 1.00 ALDH1A1 (0.56) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL12337162 1.00 ALDH1A1 (0.56) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL13498558 1.00 ALDH1A1 (0.56) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL16076955 1.00 ALDH1A1 (0.56) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL20626631 1.00 ALDH1A1 (0.56) ALDH1A1THRBMAPK1CD69SMN1; SMN2
SCHEMBL13541586 1.00 ALDH1A1 (0.56) ALDH1A1THRBMAPK1CD69SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230346816-A1 COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTION THERAPEUTIKOS, INC. 2023-11-02 — — US disclosed
US-20230201183-A1 METHODS TO SYNERGISTICALLY ENHANCE MULTIPLE CELLULAR PROTEOSTASIS PATHWAYS TO TREAT NEURODEGENERATION AND STORAGE DISEASES NORTHWESTERN UNIVERSITY 2023-06-29 — — US disclosed
US-9981059-B2 Sugar chain-polypeptide complex GLYTECH, INC. (JP) 2018-05-29 — — US disclosed
US-20170119844-A1 HEMOSTATIC PHARMACEUTICAL COMPOSITION OTSUKA CHEMICAL CO., LTD. (JP) 2017-05-04 — — US disclosed
WO-2016152980-A1 OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE CONSTRUCT USING SAME, AND METHODS FOR PRODUCING THESE 国立大学法人岐阜大学 2016-09-29 — — WO disclosed
US-20160129150-A1 SUGAR CHAIN-POLYPEPTIDE COMPLEX GLYTECH, INC. (JP) 2016-05-12 — — US disclosed
US-9215888-B2 Nutritional composition made using isolated organic matter DUOIBES, ALBERT R. 2015-12-22 — — US disclosed
US-20150182549-A1 METHOD FOR ENZYMATIC GLYCOSYLATION OF OLIGOSACCHARIDES FROM MAMMALIAN ANIMAL MILK GLYCOM A/S (DK) 2015-07-02 — — US disclosed
US-8974793-B2 Methods and systems for inducing immunologic tolerance to non-self antigens THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2015-03-10 — — US disclosed
US-20130295163-A1 NON-REDUCING END MODIFIED GLUCAN, METHOD FOR PRODUCING SAME, AND USE THEREOF EZAKI GLICO CO., LTD. (JP) 2013-11-07 — — US disclosed
US-8431551-B2 Nutritional composition made using isolated organic matter DUOIBES, ALBERT R 2013-04-30 — — US disclosed
US-20120264924-A1 Glycorandomization and Production of Novel Novobiocin Analogs WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-10-18 — — US disclosed
US-8198419-B2 Glycorandomization and production of novel erythromycin analogs WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-06-12 — — US disclosed
US-20120021056-A1 Methods and Systems for Inducing Immunologic Tolerance to Non-Self Antigens THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2012-01-26 — — US disclosed
US-20110171319-A1 NUTRITIONAL COMPOSITION MADE USING ISOLATED ORGANIC MATTER DUOIBES, ALBERT R 2011-07-14 — — US disclosed
US-20110124850-A1 Glycorandomization and Production of Novel Vancomycin Analogs THORSON JON 2011-05-26 — — US disclosed
US-20080268504-A1 Glycorandomization and Production of Novel Vancomycin Analogs WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-10-30 — — US disclosed
US-20070173438-A1 [PSI[CH2NH]PG4] glycopeptide antibiotic analogs THE SCRIPPS RESEARCH INSTITUTE (US) 2007-07-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230201183-A1 METHODS TO SYNERGISTICALLY ENHANCE MULTIPLE CELLULAR PROTEOSTASIS PATHWAYS TO TREAT NEURODEGENERATION AND STORAGE DISEASES HSPA5, GBA1, SNCA ALDH1A1 4027/4885THRB 3467/4885MAPK1 2264/4885
US-20120021056-A1 Methods and Systems for Inducing Immunologic Tolerance to Non-Self Antigens CD47, CD74, HLA-C ALDH1A1 3800/4885THRB 4450/4885MAPK1 2294/4885
US-20110124850-A1 Glycorandomization and Production of Novel Vancomycin Analogs NMT1, NMT2, B3GNT2 ALDH1A1 1950/4885THRB 4071/4885MAPK1 4161/4885
US-20160129150-A1 SUGAR CHAIN-POLYPEPTIDE COMPLEX IAPP, ENPEP, QPCTL ALDH1A1 4182/4885THRB 3049/4885MAPK1 1901/4885
US-20150182549-A1 METHOD FOR ENZYMATIC GLYCOSYLATION OF OLIGOSACCHARIDES FROM MAMMALIAN ANIMAL MILK GALE, SI, FUT6 ALDH1A1 786/4885THRB 1340/4885MAPK1 3663/4885
US-20070173438-A1 [PSI[CH2NH]PG4] glycopeptide antibiotic analogs RPN2, PA2G4, DDOST ALDH1A1 4039/4885THRB 3301/4885MAPK1 4241/4885
US-20230346816-A1 COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTION ACE, ACE2, MAVS ALDH1A1 1745/4885THRB 4270/4885MAPK1 3248/4885
US-20170119844-A1 HEMOSTATIC PHARMACEUTICAL COMPOSITION F12, FGB, HABP2 ALDH1A1 3078/4885THRB 3567/4885MAPK1 3851/4885
US-20110171319-A1 NUTRITIONAL COMPOSITION MADE USING ISOLATED ORGANIC MATTER SLC25A11, FABP2, FABP4 ALDH1A1 3048/4885THRB 4832/4885MAPK1 3828/4885
US-20120264924-A1 Glycorandomization and Production of Novel Novobiocin Analogs NMT2, NMT1, NAMPT ALDH1A1 2259/4885THRB 4386/4885MAPK1 4166/4885
US-20080268504-A1 Glycorandomization and Production of Novel Vancomycin Analogs NMT1, NMT2, B3GNT2 ALDH1A1 1797/4885THRB 4031/4885MAPK1 4077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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