Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 11/20 | 0.56 |
| ▸ | GRPR | P30550 | 1/20 | 0.54 |
| ▸ | REN | P00797 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18854323 | 0.95 | GHSR (0.59) | GHSRREN | |
| SCHEMBL18857765 | 0.94 | GHSR (0.51) | GHSRGRPR | |
| SCHEMBL18854269 | 0.93 | GHSR (0.60) | GHSRGRPRREN | |
| SCHEMBL18854322 | 0.88 | IL23R (0.60) | GHSRGRPRREN | |
| SCHEMBL18854328 | 0.85 | GHSR (0.49) | GHSRGRPR | |
| SCHEMBL18854276 | 0.84 | GHSR (0.47) | GHSRGRPR | |
| SCHEMBL30824287 | 0.83 | GHSR (0.63) | GHSR | |
| SCHEMBL18854326 | 0.83 | GHSR (0.56) | GHSRREN | |
| SCHEMBL18854334 | 0.83 | GHSR (0.56) | GHSRREN | |
| SCHEMBL18862442 | 0.83 | GHSR (0.56) | GHSRREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017083368-A9 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | PFIZER INC. (US) | 2018-04-12 | — | — | WO | disclosed |
| US-20170137801-A1 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-05-18 | — | — | US | disclosed |
| WO-2017083368-A1 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | PFIZER INC. (US) | 2017-05-18 | — | — | WO | disclosed |