Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18231650 | 0.98 | ALDH1A1 (0.50) | ALDH1A1CTSBCTSKKDRGAA | |
| Hydrochloric Acid SCHEMBL4590342 | 0.83 | KDR (0.53) | ALDH1A1CTSBCTSKKDRMEN1 | |
| SCHEMBL2828462 | 0.83 | KDR (0.53) | ALDH1A1CTSBCTSKKDRMEN1 | |
| SCHEMBL18855631 | 0.80 | CTSB (0.45) | ALDH1A1CTSBCTSKKDRMEN1 | |
| SCHEMBL16497158 | 0.78 | CTSB (0.54) | ALDH1A1CTSBCTSKKDRMEN1 | |
| SCHEMBL21227987 | 0.76 | KDR (0.46) | CTSBCTSKKDRPARP1TNK1 | |
| SCHEMBL12683534 | 0.74 | CTSB (0.41) | ALDH1A1CTSBCTSKKDRKDM4E | |
| SCHEMBL12066117 | 0.73 | KDR (0.42) | CTSBCTSKKDRPARP1TNK1 | |
| SCHEMBL28120145 | 0.73 | ALDH1A1 (0.59) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL28120163 | 0.73 | ALDH1A1 (0.59) | ALDH1A1GAAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3950692-A1 | NOVEL TRICYCLIC COMPOUNDS | AbbVie Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| EP-2506716-B1 | NOVEL TRICYCLIC COMPOUNDS | ABBVIE INC (US) | 2017-05-17 | — | — | EP | disclosed |