Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17827121 | 0.72 | PIK3CB (0.34) | — | |
| SCHEMBL18855873 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL1536094 | 0.71 | L3MBTL1 (0.50) | ALDH1A1HPGD | |
| SCHEMBL18855397 | 0.69 | — | — | |
| SCHEMBL12032318 | 0.67 | PIK3C3 (0.32) | — | |
| SCHEMBL19250614 | 0.63 | — | — | |
| SCHEMBL18855569 | 0.62 | SMN1; SMN2 (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2318732 | 0.62 | DGAT1 (0.38) | NPC1 | |
| SCHEMBL22620879 | 0.61 | MGAM (0.32) | NPC1RAB9A | |
| SCHEMBL1536777 | 0.59 | L3MBTL1 (0.51) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3950692-A1 | NOVEL TRICYCLIC COMPOUNDS | AbbVie Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| EP-2506716-B1 | NOVEL TRICYCLIC COMPOUNDS | ABBVIE INC (US) | 2017-05-17 | — | — | EP | disclosed |