Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18856285 | 0.84 | NPSR1 (0.47) | MAPTCYP1A2CYP2D6KMT2ACHRM2 | |
| SCHEMBL17011233 | 0.83 | MAPT (0.48) | MAPTCYP1A2CYP2D6KMT2ACHRM2 | |
| SCHEMBL6894286 | 0.83 | MAPT (0.48) | MAPTCYP1A2CYP2D6KMT2ACHRM2 | |
| SCHEMBL18388288 | 0.81 | MAPT (0.43) | MAPTCYP1A2CYP2D6KMT2ACHRM2 | |
| SCHEMBL6898376 | 0.80 | MAPT (0.52) | MAPTCYP1A2CYP2D6KMT2ACHRM2 | |
| SCHEMBL28044958 | 0.78 | MAPT (0.50) | MAPTCYP1A2CYP2D6KMT2ACHRM2 | |
| Hydrochloric Acid SCHEMBL28209912 | 0.78 | KMT2A (0.50) | MAPTCYP1A2CYP2D6KMT2ACHRM2 | |
| SCHEMBL18388298 | 0.77 | PIN1 (0.43) | MAPTKMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL12120740 | 0.77 | LMNA (0.45) | MAPTKMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL19359885 | 0.77 | LMNA (0.45) | MAPTKMT2ACHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650341-B2 | Process for synthesizing oxidized lactam compounds | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-05-16 | — | — | US | disclosed |