Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 4/20 | 0.37 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14802348 | 0.88 | G6PD (0.33) | G6PD | |
| SCHEMBL15293425 | 0.88 | G6PD (0.33) | G6PD | |
| SCHEMBL14864284 | 0.88 | G6PD (0.33) | G6PD | |
| SCHEMBL18723048 | 0.88 | LGALS8 (0.43) | LGALS8GAAOGA | |
| SCHEMBL13482776 | 0.88 | LGALS8 (0.43) | LGALS8GAAOGA | |
| SCHEMBL23723836 | 0.88 | LGALS8 (0.43) | LGALS8GAAOGA | |
| SCHEMBL16504207 | 0.88 | LGALS8 (0.43) | LGALS8GAAOGA | |
| SCHEMBL20033536 | 0.88 | LGALS8 (0.43) | LGALS8GAAOGA | |
| SCHEMBL14864297 | 0.88 | LGALS8 (0.43) | LGALS8GAAOGA | |
| SCHEMBL17256295 | 0.88 | LGALS8 (0.43) | LGALS8GAAOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017083368-A9 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | PFIZER INC. (US) | 2018-04-12 | — | — | WO | disclosed |
| WO-2017083368-A1 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | PFIZER INC. (US) | 2017-05-18 | — | — | WO | disclosed |