Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | CASP3 | P42574 | 1/20 | 0.68 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.68 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.68 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.66 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13727246 | 1.00 | MEN1 (0.68) | MEN1KMT2AMAPK1POLBCASP3 | |
| SCHEMBL13727245 | 1.00 | MEN1 (0.68) | MEN1KMT2AMAPK1POLBCASP3 | |
| SCHEMBL17051283 | 0.86 | MYC (0.76) | MEN1KMT2AMAPK1POLBCASP3 | |
| SCHEMBL24129903 | 0.85 | CISD1 (0.67) | MEN1KMT2AMAPK1POLBCASP3 | |
| SCHEMBL2447134 | 0.85 | CISD1 (0.67) | MEN1KMT2AMAPK1POLBCASP3 | |
| SCHEMBL2447131 | 0.85 | CISD1 (0.67) | MEN1KMT2AMAPK1POLBCASP3 | |
| SCHEMBL21296297 | 0.85 | MEN1 (0.64) | MEN1KMT2AMAPK1POLBCASP3 | |
| SCHEMBL21296295 | 0.85 | MEN1 (0.64) | MEN1KMT2AMAPK1POLBCASP3 | |
| SCHEMBL14777217 | 0.85 | PDE4B (0.76) | MEN1KMT2AMAPK1POLBCASP3 | |
| SCHEMBL14777216 | 0.85 | PDE4B (0.76) | MEN1KMT2AMAPK1POLBCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137473-A1 | FLUOROGEN ACTIVATING AND SHIFTING TAG (FAST) | PARIS SCIENCES ET LETTRES (FR) | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137473-A1 | FLUOROGEN ACTIVATING AND SHIFTING TAG (FAST) | IK, FES, ATIC | MEN1 3159/4885KMT2A 2727/4885MAPK1 1061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.