SCHEMBL13727246

SCHEMBL13727246

CCN1C(=O)C(=Cc2ccc(O)cc2)SC1=S

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 7/20 0.68
▸ KMT2A Q03164 7/20 0.68
▸ MAPK1 P28482 3/20 0.68
▸ POLB P06746 2/20 0.68
▸ CASP3 P42574 1/20 0.68
▸ SENP8 Q96LD8 1/20 0.68
▸ SENP7 Q9BQF6 1/20 0.68
▸ SENP6 Q9GZR1 1/20 0.68
▸ PDE4B Q07343 2/20 0.66
▸ DNM1 Q05193 1/20 0.61
▸ ALDH1A1 P00352 2/20 0.60
▸ CRHBP P24387 1/20 0.60
▸ CRHR2 Q13324 1/20 0.60
▸ MAPT P10636 4/20 0.59
▸ USP2 O75604 1/20 0.59
▸ TDP1 Q9NUW8 1/20 0.59
▸ RECQL P46063 1/20 0.59
▸ MAOA P21397 1/20 0.58
▸ MAOB P27338 1/20 0.58
▸ MCL1 Q07820 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18857854 1.00 MEN1 (0.68) MEN1KMT2AMAPK1POLBCASP3
SCHEMBL13727245 1.00 MEN1 (0.68) MEN1KMT2AMAPK1POLBCASP3
SCHEMBL17051283 0.86 MYC (0.76) MEN1KMT2AMAPK1POLBCASP3
SCHEMBL24129903 0.85 CISD1 (0.67) MEN1KMT2AMAPK1POLBCASP3
SCHEMBL2447134 0.85 CISD1 (0.67) MEN1KMT2AMAPK1POLBCASP3
SCHEMBL2447131 0.85 CISD1 (0.67) MEN1KMT2AMAPK1POLBCASP3
SCHEMBL21296297 0.85 MEN1 (0.64) MEN1KMT2AMAPK1POLBCASP3
SCHEMBL21296295 0.85 MEN1 (0.64) MEN1KMT2AMAPK1POLBCASP3
SCHEMBL14777217 0.85 PDE4B (0.76) MEN1KMT2AMAPK1POLBCASP3
SCHEMBL14777216 0.85 PDE4B (0.76) MEN1KMT2AMAPK1POLBCASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2704578-A2 IMPROVED HONEYBEE REPELLENTS AND USES THEREOF Inscent, Inc. (US) 2014-03-12 — — EP claimed
WO-2012151556-A2 IMPROVED HONEYBEE REPELLENTS AND USES THEREOF INSCENT, INC. (US) 2012-11-08 — — WO claimed
US-11963527-B2 Compounds, compositions, and methods for altering insect and organism behavior BASF CORPORATION (US) 2024-04-23 — — US disclosed
US-20190104732-A1 Compounds, Compositions, and Methods for Altering Insect and Organism Behavior BASF CORPORATION 2019-04-11 — — US disclosed
US-10098352-B2 Honeybee repellents and uses thereof INSCENT, INC. (US) 2018-10-16 — — US disclosed
US-20160330960-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2016-11-17 — — US disclosed
US-9439434-B2 Honeybee repellents and uses thereof INSCENT, INC. (US) 2016-09-13 — — US disclosed
EP-2704578-B1 USE OF HONEYBEE REPELLENTS INSCENT INC (US) 2016-08-31 — — EP disclosed
EP-3027022-A2 COMPOUNDS, COMPOSITIONS, AND METHODS FOR REPELLING AN INSECT FROM AN AREA, ARTICLE, AND/OR STRUCTURE Bayer CropScience LP (US) 2016-06-08 — — EP disclosed
US-20160029628-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR REPELLING AN INSECT FROM AN AREA,ARTICLE, AND/OR STRUCTURE BAYER CROPSCIENCE LP (US) 2016-02-04 — — US disclosed
EP-2967041-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR ALTERING INSECT AND ORGANISM BEHAVIOR Bayer CropScience LP (US) 2016-01-20 — — EP disclosed
US-20150257384-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR ALTERING INSECT AND ORGANISM BEHAVIOR BASF CORPORATION 2015-09-17 — — US disclosed
WO-2014146145-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR ALTERING INSECT AND ORGANISM BEHAVIOR BAYER CROPSCIENCE LP (US) 2014-09-18 — — WO disclosed
WO-2014146143-A2 COMPOUNDS, COMPOSITIONS, AND METHODS FOR REPELLING AN INSECT FROM AN AREA, ARTICLE, AND/OR STRUCTURE BAYER CROPSCIENCE LP (US) 2014-09-18 — — WO disclosed
US-20140155261-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2014-06-05 — — US disclosed
EP-2704578-A2 IMPROVED HONEYBEE REPELLENTS AND USES THEREOF Inscent, Inc. (US) 2014-03-12 — — EP disclosed
WO-2012151556-A2 IMPROVED HONEYBEE REPELLENTS AND USES THEREOF INSCENT, INC. (US) 2012-11-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160029628-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR REPELLING AN INSECT FROM AN AREA,ARTICLE, AND/OR STRUCTURE ACHE, BCHE, SGMS1 MEN1 592/4885KMT2A 1629/4885MAPK1 3564/4885
US-20160330960-A1 Honeybee Repellents and Uses Thereof ACHE, AHNAK, L3MBTL3 MEN1 2382/4885KMT2A 794/4885MAPK1 3847/4885
US-10098352-B2 Honeybee repellents and uses thereof ACHE, AHNAK, L3MBTL3 MEN1 2382/4885KMT2A 794/4885MAPK1 3847/4885
US-11963527-B2 Compounds, compositions, and methods for altering insect and organism behavior ACHE, DDT, MGLL MEN1 389/4885KMT2A 1063/4885MAPK1 4396/4885
US-20150257384-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR ALTERING INSECT AND ORGANISM BEHAVIOR ACHE, DDT, MGLL MEN1 389/4885KMT2A 1063/4885MAPK1 4396/4885
US-20140155261-A1 Honeybee Repellents and Uses Thereof ACHE, AHNAK, L3MBTL3 MEN1 2382/4885KMT2A 794/4885MAPK1 3847/4885
US-20190104732-A1 Compounds, Compositions, and Methods for Altering Insect and Organism Behavior ACHE, DDT, MGLL MEN1 389/4885KMT2A 1063/4885MAPK1 4396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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