SCHEMBL18860587

SCHEMBL18860587

CP(=O)(O)c1ccc(Br)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 5/20 0.42
CA12 O43570 4/20 0.42
MMP9 P14780 2/20 0.42
MMP8 P22894 2/20 0.42
MMP14 P50281 2/20 0.42
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.41
CA14 Q9ULX7 4/20 0.41
CYP2A6 P11509 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
ALOX15 P16050 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CA9 Q16790 2/20 0.37
HPGD P15428 1/20 0.37
OGG1 O15527 1/20 0.37
ESR1 P03372 1/20 0.37
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL601374 0.87 TSHR (0.50) LMNATSHRALOX15HPGDESR1
SCHEMBL345063 0.84 LMNA (0.48) LMNATSHRHPGDESR1CA2
SCHEMBL31015497 0.84 TSHR (0.48) LMNATSHRALOX15HPGDESR1
SCHEMBL345474 0.84 TSHR (0.48) LMNATSHRALOX15HPGDESR1
SCHEMBL344702 0.84 TSHR (0.48) LMNATSHRALOX15HPGDESR1
SCHEMBL3361462 0.79 CA2 (0.55) MMP2CA12MMP9MMP8MMP14
SCHEMBL11916201 0.79 CYP2A6 (0.44) MMP2CA12MMP9MMP8MMP14
SCHEMBL13713762 0.79 CA2 (0.55) LMNATSHRALDH1A1HPGDESR1
SCHEMBL11601777 0.79 HPGD (0.59) MMP2CA12MMP9MMP8MMP14
SCHEMBL2696961 0.79 TSHR (0.56) MMP2CA12MMP9MMP8MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240147841-A1 Organic Semiconductive Layer Comprising Phosphine Oxide Compounds NOVALED GMBH (DE) 2024-05-02 US disclosed
US-11950496-B2 Organic semiconductive layer comprising phosphine oxide compounds NOVALED GMBH (DE) 2024-04-02 US disclosed
EP-3381068-B1 ORGANIC SEMICONDUCTIVE LAYER COMPRISING PHOSPHINE OXIDE COMPOUNDS NOVALED GMBH (DE) 2021-12-22 EP disclosed
EP-3406617-B1 USE OF PHOSPHINE OXIDE COMPOUNDS IN A SEMICONDUCTING LAYER COMPRISED IN AN ELECTRONIC DEVICE NOVALED GMBH (DE) 2021-03-24 EP disclosed
EP-3406617-A1 USE OF PHOSPHINE OXIDE COMPOUNDS IN A SEMICONDUCTING LAYER COMPRISED IN AN ELECTRONIC DEVICE Novaled GmbH (DE) 2018-11-28 EP disclosed
US-20180337339-A1 Organic Semiconductive Layer Comprising Phosphine Oxide Compounds NOVALED GMBH (DE) 2018-11-22 US disclosed
EP-3171418-A1 ORGANIC SEMICONDUCTIVE LAYER COMPRISING PHOSPHINE OXIDE COMPOUNDS Novaled GmbH (DE) 2017-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240147841-A1 Organic Semiconductive Layer Comprising Phosphine Oxide Compounds ALK, OR10J3, CCNT1 MMP2 4692/4885CA12 2184/4885MMP9 2130/4885
US-20180337339-A1 Organic Semiconductive Layer Comprising Phosphine Oxide Compounds ALK, OR10J3, C1S MMP2 4673/4885CA12 2600/4885MMP9 2211/4885
US-11950496-B2 Organic semiconductive layer comprising phosphine oxide compounds ALK, OR10J3, C1S MMP2 4673/4885CA12 2600/4885MMP9 2211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.