Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.48 |
| ▸ | GABRE | P78334 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886149 | 1.00 | LMNA (0.48) | LMNAPLGPLATTSHRGABRP | |
| Hydrochloric Acid SCHEMBL11815542 | 0.97 | LMNA (0.46) | LMNAPLGPLATTSHRGABRP | |
| SCHEMBL26833 | 0.84 | TSHR (0.61) | LMNAPLGPLATTSHRGABRP | |
| SCHEMBL329128 | 0.84 | TSHR (0.61) | LMNAPLGPLATTSHRGABRP | |
| Cyclopropane Carboxylic Acid SCHEMBL32889332 | 0.84 | — | — | |
| Cyclopropane Carboxylic Acid SCHEMBL5499291 | 0.84 | — | — | |
| SCHEMBL36093 | 0.84 | TSHR (0.61) | LMNAPLGPLATTSHRGABRP | |
| Cyclopropane Carboxylic Acid SCHEMBL10800712 | 0.84 | — | — | |
| Cyclopropane Carboxylic Acid SCHEMBL4643 | 0.84 | — | — | |
| SCHEMBL196124 | 0.84 | TSHR (0.61) | LMNAPLGPLATTSHRGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105546-A1 | SPIROTROPANE COMPOUNDS | VIROCHEM PHARMA INC. (CA) | 2011-05-05 | — | — | US | disclosed |
| WO-2008087188-A2 | PEPTIDES FOR USE IN THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2008-07-24 | — | — | WO | disclosed |
| EP-0688752-B1 | Trifluoro-2-(trans-4-substituted cyclohexyl) ethylenes and process for their production | ASAHI GLASS CO LTD (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5621147-A | LIQUID CRYSTAL INTERMEDIATES | ASAHI GLASS COMPANY LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0688752-A1 | Trifluoro-2-(trans-4-substituted cyclohexyl) ethylenes and process for their production | ASAHI GLASS COMPANY LTD. (JP) | 1995-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105546-A1 | SPIROTROPANE COMPOUNDS | CCR5, CXCR1, CXCR2 | LMNA 2735/4885PLG 2909/4885PLAT 3436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.