Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 9/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18857602 | 0.87 | REN (0.64) | RENERAP2ERAP1LNPEPHRH1 | |
| SCHEMBL18862365 | 0.86 | REN (0.67) | RENERAP2ERAP1LNPEPHRH1 | |
| SCHEMBL22722179 | 0.86 | REN (0.65) | RENERAP2ERAP1LNPEPHRH1 | |
| SCHEMBL18862235 | 0.86 | REN (0.65) | RENERAP2ERAP1LNPEPHRH1 | |
| SCHEMBL18862059 | 0.85 | REN (0.54) | RENACE2ERAP2ERAP1LNPEP | |
| SCHEMBL18862087 | 0.85 | HRH1 (0.51) | RENACE2HRH1 | |
| SCHEMBL18857369 | 0.84 | REN (0.57) | RENACE2HRH1CTSBCTSK | |
| SCHEMBL18862444 | 0.84 | REN (0.55) | RENERAP2ERAP1LNPEPHRH1 | |
| SCHEMBL7295664 | 0.80 | HRH3 (0.51) | CTSB | |
| SCHEMBL20048702 | 0.80 | REN (0.53) | RENACE2ERAP2ERAP1LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137801-A1 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-05-18 | — | — | US | disclosed |