Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 14/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18854266 | 0.87 | REN (0.63) | RENHRH1SLC15A2CTSBCTSK | |
| SCHEMBL18862332 | 0.87 | REN (0.69) | RENHRH1SLC15A2 | |
| SCHEMBL18854269 | 0.84 | GHSR (0.60) | REN | |
| SCHEMBL18862086 | 0.84 | REN (0.51) | RENHRH1CTSBCTSKACE2 | |
| SCHEMBL18854323 | 0.84 | GHSR (0.59) | REN | |
| SCHEMBL20868190 | 0.82 | REN (0.60) | RENHRH1SLC15A2 | |
| SCHEMBL18862336 | 0.82 | REN (0.59) | RENHRH1CTSBCTSKACE2 | |
| SCHEMBL18854331 | 0.81 | GHSR (0.56) | REN | |
| SCHEMBL18862362 | 0.81 | REN (0.63) | RENHRH1 | |
| SCHEMBL28042757 | 0.78 | SLC15A2 (0.70) | RENSLC15A2ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017083368-A1 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | PFIZER INC. (US) | 2017-05-18 | — | — | WO | disclosed |